DNAzyme-Based Lithium-Selective Imaging Reveals Higher Lithium Accumulation in Bipolar Disorder Patient-Derived Neurons

[Image: see text] Lithium has been a drug for bipolar disorders (BD) for over 70 years; however, its usage has been limited by its narrow therapeutic window (between 0.6 and 1.2 mM). Understanding the cellular distribution of lithium ions (Li(+)) in patient cells will offer deep insight into this li...

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Detalles Bibliográficos
Autores principales: McGhee, Claire E., Yang, Zhenglin, Guo, Weijie, Wu, Yuting, Lyu, Mingkuan, DeLong, Cynthia J., Hong, Shanni, Ma, Yuan, McInnis, Melvin G., O’Shea, K. Sue, Lu, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8614110/
https://www.ncbi.nlm.nih.gov/pubmed/34841055
http://dx.doi.org/10.1021/acscentsci.1c00843

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