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A Hematological Travesty in the Setting of Alcohol Use Disorder and Liver Cirrhosis

Excessive ethanol consumption is associated with an increased risk of developing health complications, especially in individuals with pre-existing thrombocytopenia and cirrhosis. Here, we describe a case of a patient with a history of alcoholic cirrhosis, hypertension, and thrombocytopenia, presenti...

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Autores principales: Amidon, Ryan F, Ordookhanian, Christ, Liu, Elizabeth D, Abdallah, Omar, Kaloostian, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8614183/
https://www.ncbi.nlm.nih.gov/pubmed/34858749
http://dx.doi.org/10.7759/cureus.19096
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author Amidon, Ryan F
Ordookhanian, Christ
Liu, Elizabeth D
Abdallah, Omar
Kaloostian, Paul
author_facet Amidon, Ryan F
Ordookhanian, Christ
Liu, Elizabeth D
Abdallah, Omar
Kaloostian, Paul
author_sort Amidon, Ryan F
collection PubMed
description Excessive ethanol consumption is associated with an increased risk of developing health complications, especially in individuals with pre-existing thrombocytopenia and cirrhosis. Here, we describe a case of a patient with a history of alcoholic cirrhosis, hypertension, and thrombocytopenia, presenting with significant decline following an incidence of binge drinking. Radiography identified a large non-lobar intraparenchymal hemorrhage. However, due to severe thrombocytopenia that was unresponsive to platelet therapy, the possibility of pursuing any form of surgical intervention was negated. Surgical contraindication and a lack of response to subsequent medical management contributed to the family’s decision to opt for conservative medical treatment and comfort care. This case showcases the potential for liver cirrhosis in the setting of chronic alcohol use disorder to pave the way for terminal intracerebral hemorrhage.
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spelling pubmed-86141832021-12-01 A Hematological Travesty in the Setting of Alcohol Use Disorder and Liver Cirrhosis Amidon, Ryan F Ordookhanian, Christ Liu, Elizabeth D Abdallah, Omar Kaloostian, Paul Cureus Emergency Medicine Excessive ethanol consumption is associated with an increased risk of developing health complications, especially in individuals with pre-existing thrombocytopenia and cirrhosis. Here, we describe a case of a patient with a history of alcoholic cirrhosis, hypertension, and thrombocytopenia, presenting with significant decline following an incidence of binge drinking. Radiography identified a large non-lobar intraparenchymal hemorrhage. However, due to severe thrombocytopenia that was unresponsive to platelet therapy, the possibility of pursuing any form of surgical intervention was negated. Surgical contraindication and a lack of response to subsequent medical management contributed to the family’s decision to opt for conservative medical treatment and comfort care. This case showcases the potential for liver cirrhosis in the setting of chronic alcohol use disorder to pave the way for terminal intracerebral hemorrhage. Cureus 2021-10-28 /pmc/articles/PMC8614183/ /pubmed/34858749 http://dx.doi.org/10.7759/cureus.19096 Text en Copyright © 2021, Amidon et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Emergency Medicine
Amidon, Ryan F
Ordookhanian, Christ
Liu, Elizabeth D
Abdallah, Omar
Kaloostian, Paul
A Hematological Travesty in the Setting of Alcohol Use Disorder and Liver Cirrhosis
title A Hematological Travesty in the Setting of Alcohol Use Disorder and Liver Cirrhosis
title_full A Hematological Travesty in the Setting of Alcohol Use Disorder and Liver Cirrhosis
title_fullStr A Hematological Travesty in the Setting of Alcohol Use Disorder and Liver Cirrhosis
title_full_unstemmed A Hematological Travesty in the Setting of Alcohol Use Disorder and Liver Cirrhosis
title_short A Hematological Travesty in the Setting of Alcohol Use Disorder and Liver Cirrhosis
title_sort hematological travesty in the setting of alcohol use disorder and liver cirrhosis
topic Emergency Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8614183/
https://www.ncbi.nlm.nih.gov/pubmed/34858749
http://dx.doi.org/10.7759/cureus.19096
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