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PPARα, δ and FOXO1 Gene Silencing Overturns Palmitate-Induced Inhibition of Pyruvate Oxidation Differentially in C2C12 Myotubes

SIMPLE SUMMARY: Frequent high-dietary fat intake increases muscle lipid use and reduces muscle carbohydrate use, thereby inducing metabolic inflexibility. The latter term can be described as a poor muscle biochemical and molecular response to increased availability of insulin, which in the long term...

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Detalles Bibliográficos
Autores principales:	Chien, Hung-Che, Constantin, Despina, Greenhaff, Paul L., Constantin-Teodosiu, Dumitru
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8614693/ https://www.ncbi.nlm.nih.gov/pubmed/34827089 http://dx.doi.org/10.3390/biology10111098

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