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Bone Marrow Microenvironment in Light-Chain Amyloidosis: In Vitro Expansion and Characterization of Mesenchymal Stromal Cells

Immunoglobulin light-chain amyloidosis (AL) is caused by misfolded light chains produced by a small B cell clone. Mesenchymal stromal cells (MSCs) have been reported to affect plasma cell behavior. We aimed to characterize bone marrow (BM)-MSCs from AL patients, considering functional aspects, such...

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Detalles Bibliográficos
Autores principales: Valsecchi, Chiara, Croce, Stefania, Maltese, Alice, Montagna, Lorenza, Lenta, Elisa, Nevone, Alice, Girelli, Maria, Milani, Paolo, Bosoni, Tiziana, Massa, Margherita, Abbà, Carlotta, Campanelli, Rita, Ripepi, Jessica, De Silvestri, Annalisa, Carolei, Adriana, Palladini, Giovanni, Zecca, Marco, Nuvolone, Mario, Avanzini, Maria Antonietta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8614719/
https://www.ncbi.nlm.nih.gov/pubmed/34829752
http://dx.doi.org/10.3390/biomedicines9111523