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CRIF1 Deficiency Increased Homocysteine Production by Disrupting Dihydrofolate Reductase Expression in Vascular Endothelial Cells

Elevated plasma homocysteine levels can induce vascular endothelial dysfunction; however, the mechanisms regulating homocysteine metabolism in impaired endothelial cells are currently unclear. In this study, we deleted the essential mitoribosomal gene CR6 interacting factor 1 (CRIF1) in human umbili...

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Detalles Bibliográficos
Autores principales:	Lee, Ikjun, Piao, Shuyu, Kim, Seonhee, Nagar, Harsha, Choi, Su-Jeong, Jeon, Byeong Hwa, Oh, Sang-Ha, Irani, Kaikobad, Kim, Cuk-Seong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8614757/ https://www.ncbi.nlm.nih.gov/pubmed/34829516 http://dx.doi.org/10.3390/antiox10111645

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