Cargando…

NRF2 Activation and Downstream Effects: Focus on Parkinson’s Disease and Brain Angiotensin

Reactive oxygen species (ROS) are signalling molecules used to regulate cellular metabolism and homeostasis. However, excessive ROS production causes oxidative stress, one of the main mechanisms associated with the origin and progression of neurodegenerative disorders such as Parkinson’s disease. NR...

Descripción completa

Detalles Bibliográficos
Autores principales:	Parga, Juan A., Rodriguez-Perez, Ana I., Garcia-Garrote, Maria, Rodriguez-Pallares, Jannette, Labandeira-Garcia, Jose L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8614768/ https://www.ncbi.nlm.nih.gov/pubmed/34829520 http://dx.doi.org/10.3390/antiox10111649

Ejemplares similares

Combined cell-based therapy strategies for the treatment of Parkinson’s disease: focus on mesenchymal stromal cells
por: Rodríguez-Pallares, Jannette, et al.
Publicado: (2022)

Data on the effect of Angiotensin II and 6-hydroxydopamine on reactive oxygen species production, antioxidant gene expression and viability of different neuronal cell lines
por: Parga, Juan A., et al.
Publicado: (2018)

Dose‐dependent effect of mesenchymal stromal cells co‐grafted with dopaminergic neurons in a Parkinson's disease rat model
por: Rodriguez‐Pallares, Jannette, et al.
Publicado: (2021)

Interaction between Angiotensin Type 1, Type 2, and Mas Receptors to Regulate Adult Neurogenesis in the Brain Ventricular–Subventricular Zone
por: Garcia-Garrote, Maria, et al.
Publicado: (2019)

Brain renin-angiotensin system and dopaminergic cell vulnerability
por: Labandeira-García, Jose L., et al.
Publicado: (2014)

Brain Renin-Angiotensin System and Microglial Polarization: Implications for Aging and Neurodegeneration
por: Labandeira-Garcia, Jose L., et al.
Publicado: (2017)

Reciprocal regulation between sirtuin-1 and angiotensin-II in the substantia nigra: implications for aging and neurodegeneration
por: Diaz-Ruiz, Carmen, et al.
Publicado: (2015)

Nigral Neurons Degenerating in Parkinson's Disease Express the Angiotensin Receptor Type 1 Gene
por: Labandeira‐Garcia, Jose L., et al.
Publicado: (2022)

Angiotensin type-1 receptor and ACE2 autoantibodies in Parkinson´s disease
por: Labandeira, Carmen M., et al.
Publicado: (2022)

Microglial angiotensin type 2 receptors mediate sex‐specific expression of inflammatory cytokines independently of circulating estrogen
por: Garrido‐Gil, Pablo, et al.
Publicado: (2022)

Novel Interactions Involving the Mas Receptor Show Potential of the Renin–Angiotensin system in the Regulation of Microglia Activation: Altered Expression in Parkinsonism and Dyskinesia
por: Rivas-Santisteban, Rafael, et al.
Publicado: (2021)

Drugs Modulating Renin-Angiotensin System in COVID-19 Treatment
por: Labandeira-Garcia, Jose L., et al.
Publicado: (2022)

Angiotensin AT(1) and AT(2) receptor heteromer expression in the hemilesioned rat model of Parkinson’s disease that increases with levodopa-induced dyskinesia
por: Rivas-Santisteban, Rafael, et al.
Publicado: (2020)

Angiotensin System Autoantibodies Correlate With Routine Prognostic Indicators for COVID-19 Severity
por: Labandeira, Carmen M., et al.
Publicado: (2022)

Involvement of PPAR-γ in the neuroprotective and anti-inflammatory effects of angiotensin type 1 receptor inhibition: effects of the receptor antagonist telmisartan and receptor deletion in a mouse MPTP model of Parkinson's disease
por: Garrido-Gil, Pablo, et al.
Publicado: (2012)

Renin angiotensin system and gender differences in dopaminergic degeneration
por: Rodriguez-Perez, Ana I, et al.
Publicado: (2011)

Functional Complexes of Angiotensin-Converting Enzyme 2 and Renin-Angiotensin System Receptors: Expression in Adult but Not Fetal Lung Tissue
por: Franco, Rafael, et al.
Publicado: (2020)

Autoantibodies against ACE2 and angiotensin type-1 receptors increase severity of COVID-19
por: Rodriguez-Perez, Ana I., et al.
Publicado: (2021)

The intracellular renin-angiotensin system: Friend or foe. Some light from the dopaminergic neurons
por: Labandeira-Garcia, Jose L., et al.
Publicado: (2021)

Crosstalk between insulin-like growth factor-1 and angiotensin-II in dopaminergic neurons and glial cells: role in neuroinflammation and aging
por: Rodriguez-Perez, Ana I., et al.
Publicado: (2016)

Interactions between ibuprofen, ACE2, renin‐angiotensin system, and spike protein in the lung. Implications for COVID‐19
por: Valenzuela, Rita, et al.
Publicado: (2021)

Paracrine and Intracrine Angiotensin 1-7/Mas Receptor Axis in the Substantia Nigra of Rodents, Monkeys, and Humans
por: Costa-Besada, Maria A., et al.
Publicado: (2017)

Angiotensin Type 1 Receptor Antagonists Protect Against Alpha-Synuclein-Induced Neuroinflammation and Dopaminergic Neuron Death
por: Rodriguez-Perez, Ana I., et al.
Publicado: (2018)

Interactions between Angiotensin Type-1 Antagonists, Statins, and ROCK Inhibitors in a Rat Model of L-DOPA-Induced Dyskinesia
por: Lopez-Lopez, Andrea, et al.
Publicado: (2023)

Angiotensin Type-1 Receptor Inhibition Reduces NLRP3 Inflammasome Upregulation Induced by Aging and Neurodegeneration in the Substantia Nigra of Male Rodents and Primary Mesencephalic Cultures
por: Quijano, Aloia, et al.
Publicado: (2022)

Expression of angiotensinogen and receptors for angiotensin and prorenin in the monkey and human substantia nigra: an intracellular renin–angiotensin system in the nigra
por: Garrido-Gil, Pablo, et al.
Publicado: (2012)

Interactions Between the Serotonergic and Other Neurotransmitter Systems in the Basal Ganglia: Role in Parkinson’s Disease and Adverse Effects of L-DOPA
por: Muñoz, Ana, et al.
Publicado: (2020)

Insulin-Like Growth Factor-1 and Neuroinflammation
por: Labandeira-Garcia, Jose L., et al.
Publicado: (2017)

The intracellular angiotensin system buffers deleterious effects of the extracellular paracrine system
por: Villar-Cheda, Begoña, et al.
Publicado: (2017)

Parkinson’s disease and diabetes mellitus: common mechanisms and treatment repurposing
por: Labandeira, Carmen M., et al.
Publicado: (2022)

Importance of the Brain Angiotensin System in Parkinson's Disease
por: Wright, John W., et al.
Publicado: (2012)

Blood-brain barrier opening with focused ultrasound in Parkinson’s disease dementia
por: Gasca-Salas, Carmen, et al.
Publicado: (2021)

Glucocerebrosidase expression patterns in the non-human primate brain
por: Dopeso-Reyes, Iria G., et al.
Publicado: (2017)

Aging-related dysregulation in enteric dopamine and angiotensin system interactions: implications for gastrointestinal dysfunction in the elderly
por: Garrido-Gil, Pablo, et al.
Publicado: (2018)

Experimental data using candesartan and captopril indicate no double-edged sword effect in COVID-19
por: Pedrosa, Maria A., et al.
Publicado: (2021)

Focus on Depression in Parkinson's Disease: A Delphi Consensus of Experts in Psychiatry, Neurology, and Geriatrics
por: Agüera-Ortiz, Luis, et al.
Publicado: (2021)

Focus on Brain Angiotensin III and Aminopeptidase A in the Control of Hypertension
por: Wright, John W., et al.
Publicado: (2012)

Revisiting the Brain Renin-Angiotensin System—Focus on Novel Therapies
por: Ren, Liwei, et al.
Publicado: (2019)

NADPH-Oxidase, Rho-Kinase and Autophagy Mediate the (Pro)renin-Induced Pro-Inflammatory Microglial Response and Enhancement of Dopaminergic Neuron Death
por: Lopez-Lopez, Andrea, et al.
Publicado: (2021)

Metallothionein Is Downstream of Nrf2 and Partially Mediates Sulforaphane Prevention of Diabetic Cardiomyopathy
por: Gu, Junlian, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_p4qn07podjjj1ajifcsgfmbq7k