Cargando…
Garlic (Allium sativum L.) Bioactives and Its Role in Alleviating Oral Pathologies
Garlic (Allium sativa L.) is a bulbous flowering plant belongs to the family of Amaryllidaceae and is a predominant horticultural crop originating from central Asia. Garlic and its products are chiefly used for culinary and therapeutic purposes in many countries. Bulbs of raw garlic have been invest...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8614839/ https://www.ncbi.nlm.nih.gov/pubmed/34829718 http://dx.doi.org/10.3390/antiox10111847 |
_version_ | 1784603958322397184 |
---|---|
author | Sasi, Minnu Kumar, Sandeep Kumar, Manoj Thapa, Sandhya Prajapati, Uma Tak, Yamini Changan, Sushil Saurabh, Vivek Kumari, Shweta Kumar, Ashok Hasan, Muzaffar Chandran, Deepak Radha, Bangar, Sneh Punia Dhumal, Sangram Senapathy, Marisennayya Thiyagarajan, Anitha Alhariri, Ahmad Dey, Abhijit Singh, Surinder Prakash, Suraj Pandiselvam, Ravi Mekhemar, Mohamed |
author_facet | Sasi, Minnu Kumar, Sandeep Kumar, Manoj Thapa, Sandhya Prajapati, Uma Tak, Yamini Changan, Sushil Saurabh, Vivek Kumari, Shweta Kumar, Ashok Hasan, Muzaffar Chandran, Deepak Radha, Bangar, Sneh Punia Dhumal, Sangram Senapathy, Marisennayya Thiyagarajan, Anitha Alhariri, Ahmad Dey, Abhijit Singh, Surinder Prakash, Suraj Pandiselvam, Ravi Mekhemar, Mohamed |
author_sort | Sasi, Minnu |
collection | PubMed |
description | Garlic (Allium sativa L.) is a bulbous flowering plant belongs to the family of Amaryllidaceae and is a predominant horticultural crop originating from central Asia. Garlic and its products are chiefly used for culinary and therapeutic purposes in many countries. Bulbs of raw garlic have been investigated for their role in oral health, which are ascribed to a myriad of biologically active compounds such as alliin, allicin, methiin, S-allylcysteine (SAC), diallyl sulfide (DAS), S-ally-mercapto cysteine (SAMC), diallyl disulphide (DADS), diallyl trisulfide (DATS) and methyl allyl disulphide. A systematic review was conducted following the PRISMA statement. Scopus, PubMed, Clinicaltrials.gov, and Science direct databases were searched between 12 April 2021 to 4 September 2021. A total of 148 studies were included and the qualitative synthesis phytochemical profile of GE, biological activities, therapeutic applications of garlic extract (GE) in oral health care system, and its mechanism of action in curing various oral pathologies have been discussed. Furthermore, the safety of incorporation of GE as food supplements is also critically discussed. To conclude, GE could conceivably make a treatment recourse for patients suffering from diverse oral diseases. |
format | Online Article Text |
id | pubmed-8614839 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-86148392021-11-26 Garlic (Allium sativum L.) Bioactives and Its Role in Alleviating Oral Pathologies Sasi, Minnu Kumar, Sandeep Kumar, Manoj Thapa, Sandhya Prajapati, Uma Tak, Yamini Changan, Sushil Saurabh, Vivek Kumari, Shweta Kumar, Ashok Hasan, Muzaffar Chandran, Deepak Radha, Bangar, Sneh Punia Dhumal, Sangram Senapathy, Marisennayya Thiyagarajan, Anitha Alhariri, Ahmad Dey, Abhijit Singh, Surinder Prakash, Suraj Pandiselvam, Ravi Mekhemar, Mohamed Antioxidants (Basel) Review Garlic (Allium sativa L.) is a bulbous flowering plant belongs to the family of Amaryllidaceae and is a predominant horticultural crop originating from central Asia. Garlic and its products are chiefly used for culinary and therapeutic purposes in many countries. Bulbs of raw garlic have been investigated for their role in oral health, which are ascribed to a myriad of biologically active compounds such as alliin, allicin, methiin, S-allylcysteine (SAC), diallyl sulfide (DAS), S-ally-mercapto cysteine (SAMC), diallyl disulphide (DADS), diallyl trisulfide (DATS) and methyl allyl disulphide. A systematic review was conducted following the PRISMA statement. Scopus, PubMed, Clinicaltrials.gov, and Science direct databases were searched between 12 April 2021 to 4 September 2021. A total of 148 studies were included and the qualitative synthesis phytochemical profile of GE, biological activities, therapeutic applications of garlic extract (GE) in oral health care system, and its mechanism of action in curing various oral pathologies have been discussed. Furthermore, the safety of incorporation of GE as food supplements is also critically discussed. To conclude, GE could conceivably make a treatment recourse for patients suffering from diverse oral diseases. MDPI 2021-11-21 /pmc/articles/PMC8614839/ /pubmed/34829718 http://dx.doi.org/10.3390/antiox10111847 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Sasi, Minnu Kumar, Sandeep Kumar, Manoj Thapa, Sandhya Prajapati, Uma Tak, Yamini Changan, Sushil Saurabh, Vivek Kumari, Shweta Kumar, Ashok Hasan, Muzaffar Chandran, Deepak Radha, Bangar, Sneh Punia Dhumal, Sangram Senapathy, Marisennayya Thiyagarajan, Anitha Alhariri, Ahmad Dey, Abhijit Singh, Surinder Prakash, Suraj Pandiselvam, Ravi Mekhemar, Mohamed Garlic (Allium sativum L.) Bioactives and Its Role in Alleviating Oral Pathologies |
title | Garlic (Allium sativum L.) Bioactives and Its Role in Alleviating Oral Pathologies |
title_full | Garlic (Allium sativum L.) Bioactives and Its Role in Alleviating Oral Pathologies |
title_fullStr | Garlic (Allium sativum L.) Bioactives and Its Role in Alleviating Oral Pathologies |
title_full_unstemmed | Garlic (Allium sativum L.) Bioactives and Its Role in Alleviating Oral Pathologies |
title_short | Garlic (Allium sativum L.) Bioactives and Its Role in Alleviating Oral Pathologies |
title_sort | garlic (allium sativum l.) bioactives and its role in alleviating oral pathologies |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8614839/ https://www.ncbi.nlm.nih.gov/pubmed/34829718 http://dx.doi.org/10.3390/antiox10111847 |
work_keys_str_mv | AT sasiminnu garlicalliumsativumlbioactivesanditsroleinalleviatingoralpathologies AT kumarsandeep garlicalliumsativumlbioactivesanditsroleinalleviatingoralpathologies AT kumarmanoj garlicalliumsativumlbioactivesanditsroleinalleviatingoralpathologies AT thapasandhya garlicalliumsativumlbioactivesanditsroleinalleviatingoralpathologies AT prajapatiuma garlicalliumsativumlbioactivesanditsroleinalleviatingoralpathologies AT takyamini garlicalliumsativumlbioactivesanditsroleinalleviatingoralpathologies AT changansushil garlicalliumsativumlbioactivesanditsroleinalleviatingoralpathologies AT saurabhvivek garlicalliumsativumlbioactivesanditsroleinalleviatingoralpathologies AT kumarishweta garlicalliumsativumlbioactivesanditsroleinalleviatingoralpathologies AT kumarashok garlicalliumsativumlbioactivesanditsroleinalleviatingoralpathologies AT hasanmuzaffar garlicalliumsativumlbioactivesanditsroleinalleviatingoralpathologies AT chandrandeepak garlicalliumsativumlbioactivesanditsroleinalleviatingoralpathologies AT radha garlicalliumsativumlbioactivesanditsroleinalleviatingoralpathologies AT bangarsnehpunia garlicalliumsativumlbioactivesanditsroleinalleviatingoralpathologies AT dhumalsangram garlicalliumsativumlbioactivesanditsroleinalleviatingoralpathologies AT senapathymarisennayya garlicalliumsativumlbioactivesanditsroleinalleviatingoralpathologies AT thiyagarajananitha garlicalliumsativumlbioactivesanditsroleinalleviatingoralpathologies AT alhaririahmad garlicalliumsativumlbioactivesanditsroleinalleviatingoralpathologies AT deyabhijit garlicalliumsativumlbioactivesanditsroleinalleviatingoralpathologies AT singhsurinder garlicalliumsativumlbioactivesanditsroleinalleviatingoralpathologies AT prakashsuraj garlicalliumsativumlbioactivesanditsroleinalleviatingoralpathologies AT pandiselvamravi garlicalliumsativumlbioactivesanditsroleinalleviatingoralpathologies AT mekhemarmohamed garlicalliumsativumlbioactivesanditsroleinalleviatingoralpathologies |