Cargando…

Physical Exercise Potentially Targets Epicardial Adipose Tissue to Reduce Cardiovascular Disease Risk in Patients with Metabolic Diseases: Oxidative Stress and Inflammation Emerge as Major Therapeutic Targets

Excess epicardial adiposity, within a state of obesity and metabolic syndrome, is emerging as an important risk factor for the development of cardiovascular diseases (CVDs). Accordingly, increased epicardial fat thickness (EFT) implicates the exacerbation of pathological mechanisms involving oxidati...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nyawo, Thembeka A., Pheiffer, Carmen, Mazibuko-Mbeje, Sithandiwe E., Mthembu, Sinenhlanhla X. H., Nyambuya, Tawanda M., Nkambule, Bongani B., Sadie-Van Gijsen, Hanél, Strijdom, Hans, Tiano, Luca, Dludla, Phiwayinkosi V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8614861/ https://www.ncbi.nlm.nih.gov/pubmed/34829629 http://dx.doi.org/10.3390/antiox10111758

Ejemplares similares

A systematic review exploring the significance of measuring epicardial fat thickness in correlation to B-type natriuretic peptide levels as prognostic and diagnostic markers in patients with or at risk of heart failure
por: Nyawo, Thembeka A., et al.
Publicado: (2021)

The Potential Role of Polyphenols in Modulating Mitochondrial Bioenergetics within the Skeletal Muscle: A Systematic Review of Preclinical Models
por: Mthembu, Sinenhlanhla X. H., et al.
Publicado: (2021)

Anti-Obesity Effects of Metformin: A Scoping Review Evaluating the Feasibility of Brown Adipose Tissue as a Therapeutic Target
por: Ziqubu, Khanyisani, et al.
Publicado: (2023)

An insight into brown/beige adipose tissue whitening, a metabolic complication of obesity with the multifactorial origin
por: Ziqubu, Khanyisani, et al.
Publicado: (2023)

Natural killer cell levels in adults living with type 2 diabetes: a systematic review and meta-analysis of clinical studies
por: Mxinwa, Vuyolwethu, et al.
Publicado: (2020)

A Review on the Antidiabetic Properties of Moringa oleifera Extracts: Focusing on Oxidative Stress and Inflammation as Main Therapeutic Targets
por: Mthiyane, Fikile T., et al.
Publicado: (2022)

Corrigendum: A review on the antidiabetic properties of Moringa oleifera extracts: Focusing on oxidative stress and inflammation as main therapeutic targets
por: Mthiyane, Fikile T., et al.
Publicado: (2023)

A Meta-Analysis of the Impact of Resveratrol Supplementation on Markers of Renal Function and Blood Pressure in Type 2 Diabetic Patients on Hypoglycemic Therapy
por: Nyambuya, Tawanda M., et al.
Publicado: (2020)

N-Acetyl Cysteine Targets Hepatic Lipid Accumulation to Curb Oxidative Stress and Inflammation in NAFLD: A Comprehensive Analysis of the Literature
por: Dludla, Phiwayinkosi V., et al.
Publicado: (2020)

Drug-Induced Liver Injury: Clinical Evidence of N-Acetyl Cysteine Protective Effects
por: Ntamo, Yonela, et al.
Publicado: (2021)

Dietary Supplements Potentially Target Plasma Glutathione Levels to Improve Cardiometabolic Health in Patients with Diabetes Mellitus: A Systematic Review of Randomized Clinical Trials
por: Dludla, Phiwayinkosi V., et al.
Publicado: (2023)

N-Acetyl cysteine ameliorates hyperglycemia-induced cardiomyocyte toxicity by improving mitochondrial energetics and enhancing endogenous Coenzyme Q(9/10) levels
por: Dludla, Phiwayinkosi V., et al.
Publicado: (2019)

Vitamin C intake potentially lowers total cholesterol to improve endothelial function in diabetic patients at increased risk of cardiovascular disease: A systematic review of randomized controlled trials
por: Dludla, Phiwayinkosi V., et al.
Publicado: (2022)

T cell activation and cardiovascular risk in type 2 diabetes mellitus: a protocol for a systematic review and meta-analysis
por: Nyambuya, Tawanda M., et al.
Publicado: (2018)

Diet-Induced Obesity Promotes the Upregulation of Fas Expression on T-cells
por: Nyambuya, Tawanda Maurice, et al.
Publicado: (2021)

Isoorientin ameliorates lipid accumulation by regulating fat browning in palmitate-exposed 3T3-L1 adipocytes
por: Mazibuko-Mbeje, Sithandiwe E., et al.
Publicado: (2020)

Exploring the Comparative Efficacy of Metformin and Resveratrol in the Management of Diabetes-Associated Complications: A Systematic Review of Preclinical Studies
por: Dludla, Phiwayinkosi V., et al.
Publicado: (2020)

Rooibos Flavonoids, Aspalathin, Isoorientin, and Orientin Ameliorate Antimycin A-Induced Mitochondrial Dysfunction by Improving Mitochondrial Bioenergetics in Cultured Skeletal Muscle Cells
por: Mthembu, Sinenhlanhla X. H., et al.
Publicado: (2021)

Coenzyme Q(10) Supplementation Improves Adipokine Levels and Alleviates Inflammation and Lipid Peroxidation in Conditions of Metabolic Syndrome: A Meta-Analysis of Randomized Controlled Trials
por: Dludla, Phiwayinkosi V., et al.
Publicado: (2020)

Inflammation and Oxidative Stress in an Obese State and the Protective Effects of Gallic Acid
por: Dludla, Phiwayinkosi V., et al.
Publicado: (2018)

Pancreatic β-cell dysfunction in type 2 diabetes: Implications of inflammation and oxidative stress
por: Dludla, Phiwayinkosi V, et al.
Publicado: (2023)

The role of innate lymphoid cells and T helper cell activation in type 2 diabetic patients: a protocol for a systematic review and meta-analysis
por: Mxinwa, Vuyolwethu, et al.
Publicado: (2019)

Obesity-induced inflammation and insulin resistance: A mini-review on T-cells
por: Nyambuya, Tawanda Maurice, et al.
Publicado: (2019)

A systematic review and meta-analysis on the regulation of programmed cell death-1 on T-cells in type 2 diabetes
por: Nyambuya, Tawanda Maurice, et al.
Publicado: (2021)

Circulating innate lymphoid cell subtypes and altered cytokine profiles following an atherogenic high-fat diet
por: Mxinwa, Vuyolwethu, et al.
Publicado: (2021)

Expression of Caspase-3 in Circulating Innate Lymphoid Cells Subtypes Is Altered by Treatment with Metformin and Fluvastatin in High-Fat Diet Fed C57BL/6 Mice
por: Mxinwa, Vuyolwethu, et al.
Publicado: (2022)

The mean platelet volume and atherosclerotic cardiovascular-risk factors in adults with obesity: a systematic review and meta-analysis of observational studies
por: Nkambule, Bongani Brian, et al.
Publicado: (2022)

Orientin Improves Substrate Utilization and the Expression of Major Genes Involved in Insulin Signaling and Energy Regulation in Cultured Insulin-Resistant Liver Cells
por: Mazibuko-Mbeje, Sithandiwe E., et al.
Publicado: (2021)

Impact of Isoorientin on Metabolic Activity and Lipid Accumulation in Differentiated Adipocytes
por: Ziqubu, Khanyisani, et al.
Publicado: (2020)

The impact of immune checkpoint inhibitors in patients with chronic lymphocytic leukemia (CLL): A protocol for a systematic review and meta-analysis of randomized controlled trials
por: Ntsethe, Aviwe, et al.
Publicado: (2020)

Detrimental Effects of Lipid Peroxidation in Type 2 Diabetes: Exploring the Neutralizing Influence of Antioxidants
por: Shabalala, Samukelisiwe C., et al.
Publicado: (2022)

The impact of coenzyme Q(10) on metabolic and cardiovascular disease profiles in diabetic patients: A systematic review and meta‐analysis of randomized controlled trials
por: Dludla, Phiwayinkosi V., et al.
Publicado: (2020)

Monocyte-mediated inflammation and cardiovascular risk factors in type 2 diabetes mellitus: A systematic review and meta-analysis of pre-clinical and clinical studies
por: Mokgalaboni, Kabelo, et al.
Publicado: (2020)

Body weight and its influence on hepcidin levels in patients with type 2 diabetes: A systematic review and meta-analysis of clinical studies
por: Ndevahoma, Fransina, et al.
Publicado: (2021)

The effect of underlying inflammation on iron metabolism, cardiovascular risk and renal function in patients with type 2 diabetes
por: Ndevahoma, Fransina, et al.
Publicado: (2021)

Potential Benefits of Coffee Consumption on Improving Biomarkers of Oxidative Stress and Inflammation in Healthy Individuals and Those at Increased Risk of Cardiovascular Disease
por: Dludla, Phiwayinkosi V., et al.
Publicado: (2023)

Differential expression of glycoprotein IV on monocyte subsets following high-fat diet feeding and the impact of short-term low-dose aspirin treatment
por: Mokgalaboni, Kabelo, et al.
Publicado: (2020)

Platelet activation in adult HIV-infected patients on antiretroviral therapy: a systematic review and meta-analysis
por: Nkambule, Bongani B., et al.
Publicado: (2020)

Bioactive Properties, Bioavailability Profiles, and Clinical Evidence of the Potential Benefits of Black Pepper (Piper nigrum) and Red Pepper (Capsicum annum) against Diverse Metabolic Complications
por: Dludla, Phiwayinkosi V., et al.
Publicado: (2023)

The Combination Effect of Aspalathin and Phenylpyruvic Acid-2-O-β-d-glucoside from Rooibos against Hyperglycemia-Induced Cardiac Damage: An In Vitro Study
por: Dludla, Phiwayinkosi V., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_0qsq6po41sg8urc4otc8pgt9eo