A Comparative Analysis of Punicalagin Interaction with PDIA1 and PDIA3 by Biochemical and Computational Approaches

In a previous work, it was shown that punicalagin, an active ingredient of pomegranate, is able to bind to PDIA3 and inhibit its disulfide reductase activity. Here we provide evidence that punicalagin can also bind to PDIA1, the main expressed form of protein disulfide isomerase (PDI). In this compa...

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Detalles Bibliográficos
Autores principales: Paglia, Giuliano, Antonini, Lorenzo, Cervoni, Laura, Ragno, Rino, Sabatino, Manuela, Minacori, Marco, Rubini, Elisabetta, Altieri, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8614999/
https://www.ncbi.nlm.nih.gov/pubmed/34829762
http://dx.doi.org/10.3390/biomedicines9111533

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8614999/
https://www.ncbi.nlm.nih.gov/pubmed/34829762
http://dx.doi.org/10.3390/biomedicines9111533

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