Antimicrobial Activity of Aztreonam in Combination with Old and New β-Lactamase Inhibitors against MBL and ESBL Co-Producing Gram-Negative Clinical Isolates: Possible Options for the Treatment of Complicated Infections

Metallo-β-lactamases (MBLs) are among the most challenging bacterial enzymes to overcome. Aztreonam (ATM) is the only β-lactam not hydrolyzed by MBLs but is often inactivated by co-produced extended-spectrum β-lactamases (ESBL). We assessed the activity of the combination of ATM with old and new β-l...

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Detalles Bibliográficos
Autores principales: Morroni, Gianluca, Bressan, Raffaela, Fioriti, Simona, D’Achille, Gloria, Mingoia, Marina, Cirioni, Oscar, Di Bella, Stefano, Piazza, Aurora, Comandatore, Francesco, Mauri, Carola, Migliavacca, Roberta, Luzzaro, Francesco, Principe, Luigi, Lagatolla, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615000/
https://www.ncbi.nlm.nih.gov/pubmed/34827279
http://dx.doi.org/10.3390/antibiotics10111341

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615000/
https://www.ncbi.nlm.nih.gov/pubmed/34827279
http://dx.doi.org/10.3390/antibiotics10111341

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