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Inhibition of Peroxiredoxin 6 PLA2 Activity Decreases Oxidative Stress and the Severity of Acute Lung Injury in the Mouse Cecal Ligation and Puncture Model

The use of agents to inhibit the production of reactive oxygen species (ROS) has been proposed for the treatment of Acute Lung Injury (ALI). However, this approach also inhibits the bactericidal activity of polymorphonuclear leucocytes (PMN) and other cells, raising the possibility of aggravating lu...

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Detalles Bibliográficos
Autores principales: Fisher, Aron B., Dodia, Chandra, Tao, Jian-Qin, Feinstein, Sheldon I., Chatterjee, Shampa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615065/
https://www.ncbi.nlm.nih.gov/pubmed/34829547
http://dx.doi.org/10.3390/antiox10111676