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Where Do We Stand in Stem Cell Therapy for the Management of Diabetes Mellitus?—A Scientometric Research Trend Analysis from 1990 to 2020

Stem cell therapy has been considered a promising strategy in the management of both type I and type II diabetes mellitus (DM) because of its immunomodulatory and regenerative capability to restore the beta cell number and function. Various modalities of cellular therapy like transplantation of panc...

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Autores principales: Muthu, Sathish, Jeyaraman, Madhan, Jeyaraman, Naveen, Rajendran, Ramya Lakshmi, Gangadaran, Prakash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615097/
https://www.ncbi.nlm.nih.gov/pubmed/34821725
http://dx.doi.org/10.3390/bioengineering8110159
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author Muthu, Sathish
Jeyaraman, Madhan
Jeyaraman, Naveen
Rajendran, Ramya Lakshmi
Gangadaran, Prakash
author_facet Muthu, Sathish
Jeyaraman, Madhan
Jeyaraman, Naveen
Rajendran, Ramya Lakshmi
Gangadaran, Prakash
author_sort Muthu, Sathish
collection PubMed
description Stem cell therapy has been considered a promising strategy in the management of both type I and type II diabetes mellitus (DM) because of its immunomodulatory and regenerative capability to restore the beta cell number and function. Various modalities of cellular therapy like transplantation of pancreatic islet cells, transplantation of pancreatic ductal stem cells, and mesenchymal stromal cell transplantation have been tried, and the modality is undergoing rapid advancements that may become the reality in the near future. In the course of its evolution, it is essential to have a comprehensive summary of the progress for a greater capacity to refine our future directives. With technological developments like data mining, graphic drawing, and information analytics combined with computational statistics, visualization of scientific metrology has become a reality. With a newer perspective, we intend to use scientometric tools including text mining, co-word analysis, word frequency analysis, co-citation analysis, cluster network analysis, to perform a systematic and comprehensive analysis of the research trend in stem cell therapy in the management of DM over the past three decades (1990–2020) and to identify the future research hotspots.
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spelling pubmed-86150972021-11-26 Where Do We Stand in Stem Cell Therapy for the Management of Diabetes Mellitus?—A Scientometric Research Trend Analysis from 1990 to 2020 Muthu, Sathish Jeyaraman, Madhan Jeyaraman, Naveen Rajendran, Ramya Lakshmi Gangadaran, Prakash Bioengineering (Basel) Review Stem cell therapy has been considered a promising strategy in the management of both type I and type II diabetes mellitus (DM) because of its immunomodulatory and regenerative capability to restore the beta cell number and function. Various modalities of cellular therapy like transplantation of pancreatic islet cells, transplantation of pancreatic ductal stem cells, and mesenchymal stromal cell transplantation have been tried, and the modality is undergoing rapid advancements that may become the reality in the near future. In the course of its evolution, it is essential to have a comprehensive summary of the progress for a greater capacity to refine our future directives. With technological developments like data mining, graphic drawing, and information analytics combined with computational statistics, visualization of scientific metrology has become a reality. With a newer perspective, we intend to use scientometric tools including text mining, co-word analysis, word frequency analysis, co-citation analysis, cluster network analysis, to perform a systematic and comprehensive analysis of the research trend in stem cell therapy in the management of DM over the past three decades (1990–2020) and to identify the future research hotspots. MDPI 2021-10-26 /pmc/articles/PMC8615097/ /pubmed/34821725 http://dx.doi.org/10.3390/bioengineering8110159 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Muthu, Sathish
Jeyaraman, Madhan
Jeyaraman, Naveen
Rajendran, Ramya Lakshmi
Gangadaran, Prakash
Where Do We Stand in Stem Cell Therapy for the Management of Diabetes Mellitus?—A Scientometric Research Trend Analysis from 1990 to 2020
title Where Do We Stand in Stem Cell Therapy for the Management of Diabetes Mellitus?—A Scientometric Research Trend Analysis from 1990 to 2020
title_full Where Do We Stand in Stem Cell Therapy for the Management of Diabetes Mellitus?—A Scientometric Research Trend Analysis from 1990 to 2020
title_fullStr Where Do We Stand in Stem Cell Therapy for the Management of Diabetes Mellitus?—A Scientometric Research Trend Analysis from 1990 to 2020
title_full_unstemmed Where Do We Stand in Stem Cell Therapy for the Management of Diabetes Mellitus?—A Scientometric Research Trend Analysis from 1990 to 2020
title_short Where Do We Stand in Stem Cell Therapy for the Management of Diabetes Mellitus?—A Scientometric Research Trend Analysis from 1990 to 2020
title_sort where do we stand in stem cell therapy for the management of diabetes mellitus?—a scientometric research trend analysis from 1990 to 2020
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615097/
https://www.ncbi.nlm.nih.gov/pubmed/34821725
http://dx.doi.org/10.3390/bioengineering8110159
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