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Ethoxyquin Inhibits the Progression of Murine Ehrlich Ascites Carcinoma through the Inhibition of Autophagy and LDH

Cancer cells exhibit an increased glycolysis rate for ATP generation (the Warburg effect) to sustain an increased proliferation rate. In tumor cells, the oxidation of pyruvate in the Krebs cycle is substituted by lactate production, catalyzed by LDH. In this study, we use ethoxyquin (EQ) as a novel...

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Detalles Bibliográficos
Autores principales: Tayel, Fekria, Mahfouz, Magdy E., Salama, Afrah F., Mansour, Mohammed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615101/
https://www.ncbi.nlm.nih.gov/pubmed/34829755
http://dx.doi.org/10.3390/biomedicines9111526