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Conserved and Diversified Mechanism of Autophagy between Plants and Animals upon Various Stresses
Autophagy is a highly conserved degradation mechanism in eukaryotes, executing the breakdown of unwanted cell components and subsequent recycling of cellular material for stress relief through vacuole-dependence in plants and yeast while it is lysosome-dependent in animal manner. Upon stress, differ...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615172/ https://www.ncbi.nlm.nih.gov/pubmed/34829607 http://dx.doi.org/10.3390/antiox10111736 |
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author | Rehman, Naveed Ur Zeng, Peichun Mo, Zulong Guo, Shaoying Liu, Yunfeng Huang, Yifeng Xie, Qingjun |
author_facet | Rehman, Naveed Ur Zeng, Peichun Mo, Zulong Guo, Shaoying Liu, Yunfeng Huang, Yifeng Xie, Qingjun |
author_sort | Rehman, Naveed Ur |
collection | PubMed |
description | Autophagy is a highly conserved degradation mechanism in eukaryotes, executing the breakdown of unwanted cell components and subsequent recycling of cellular material for stress relief through vacuole-dependence in plants and yeast while it is lysosome-dependent in animal manner. Upon stress, different types of autophagy are stimulated to operate certain biological processes by employing specific selective autophagy receptors (SARs), which hijack the cargo proteins or organelles to the autophagy machinery for subsequent destruction in the vacuole/lysosome. Despite recent advances in autophagy, the conserved and diversified mechanism of autophagy in response to various stresses between plants and animals still remain a mystery. In this review, we intend to summarize and discuss the characterization of the SARs and their corresponding processes, expectantly advancing the scope and perspective of the evolutionary fate of autophagy between plants and animals. |
format | Online Article Text |
id | pubmed-8615172 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-86151722021-11-26 Conserved and Diversified Mechanism of Autophagy between Plants and Animals upon Various Stresses Rehman, Naveed Ur Zeng, Peichun Mo, Zulong Guo, Shaoying Liu, Yunfeng Huang, Yifeng Xie, Qingjun Antioxidants (Basel) Review Autophagy is a highly conserved degradation mechanism in eukaryotes, executing the breakdown of unwanted cell components and subsequent recycling of cellular material for stress relief through vacuole-dependence in plants and yeast while it is lysosome-dependent in animal manner. Upon stress, different types of autophagy are stimulated to operate certain biological processes by employing specific selective autophagy receptors (SARs), which hijack the cargo proteins or organelles to the autophagy machinery for subsequent destruction in the vacuole/lysosome. Despite recent advances in autophagy, the conserved and diversified mechanism of autophagy in response to various stresses between plants and animals still remain a mystery. In this review, we intend to summarize and discuss the characterization of the SARs and their corresponding processes, expectantly advancing the scope and perspective of the evolutionary fate of autophagy between plants and animals. MDPI 2021-10-29 /pmc/articles/PMC8615172/ /pubmed/34829607 http://dx.doi.org/10.3390/antiox10111736 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Rehman, Naveed Ur Zeng, Peichun Mo, Zulong Guo, Shaoying Liu, Yunfeng Huang, Yifeng Xie, Qingjun Conserved and Diversified Mechanism of Autophagy between Plants and Animals upon Various Stresses |
title | Conserved and Diversified Mechanism of Autophagy between Plants and Animals upon Various Stresses |
title_full | Conserved and Diversified Mechanism of Autophagy between Plants and Animals upon Various Stresses |
title_fullStr | Conserved and Diversified Mechanism of Autophagy between Plants and Animals upon Various Stresses |
title_full_unstemmed | Conserved and Diversified Mechanism of Autophagy between Plants and Animals upon Various Stresses |
title_short | Conserved and Diversified Mechanism of Autophagy between Plants and Animals upon Various Stresses |
title_sort | conserved and diversified mechanism of autophagy between plants and animals upon various stresses |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615172/ https://www.ncbi.nlm.nih.gov/pubmed/34829607 http://dx.doi.org/10.3390/antiox10111736 |
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