Two-Dimensional Gel Electrophoresis to Study the Activity of Type IIA Topoisomerases on Plasmid Replication Intermediates

SIMPLE SUMMARY: During replication, DNA molecules undergo topological changes that affect supercoiling, catenation and knotting. To better understand this process and the role of topoisomerases, the enzymes that control DNA topology in in vivo, two-dimensional agarose gel electrophoresis were used t...

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Detalles Bibliográficos
Autores principales: Cebrián, Jorge, Martínez, Victor, Hernández, Pablo, Krimer, Dora B., Fernández-Nestosa, María-José, Schvartzman, Jorge B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615216/
https://www.ncbi.nlm.nih.gov/pubmed/34827187
http://dx.doi.org/10.3390/biology10111195

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615216/
https://www.ncbi.nlm.nih.gov/pubmed/34827187
http://dx.doi.org/10.3390/biology10111195

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