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Single-Cell RNA-Sequencing Identifies Infrapatellar Fat Pad Macrophage Polarization in Acute Synovitis/Fat Pad Fibrosis and Cell Therapy

The pathogenesis and progression of knee inflammatory pathologies is modulated partly by residing macrophages in the infrapatellar fat pad (IFP), thus, macrophage polarization towards pro-inflammatory (M1) or anti-inflammatory (M2) phenotypes is important in joint disease pathologies. Alteration of...

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Detalles Bibliográficos
Autores principales: Kouroupis, Dimitrios, Best, Thomas M., Kaplan, Lee D., Correa, Diego, Griswold, Anthony J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615266/
https://www.ncbi.nlm.nih.gov/pubmed/34821732
http://dx.doi.org/10.3390/bioengineering8110166