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LW1497, an Inhibitor of Malate Dehydrogenase, Suppresses TGF-β1-Induced Epithelial-Mesenchymal Transition in Lung Cancer Cells by Downregulating Slug

LW1497 suppresses the expression of the hypoxia-inducing factor (HIF)-1α inhibiting malate dehydrogenase. Although hypoxia and HIF-1α are known to be important in cancer, LW1497 has not been therapeutically applied to cancer yet. Thus, we investigated the effect of LW1497 on the epithelial-mesenchym...

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Detalles Bibliográficos
Autores principales:	Kim, Hyun Ji, Park, Mi Kyung, Byun, Hyun Jung, Kim, Minkyoung, Kim, Boram, Yu, Lu, Nguyen, Tuan Minh, Nguyen, Thi Ha, Do, Phuong Anh, Kim, Eun Ji, Kim, Ji Hyun, Enkhtaivan, Enkhmend, Kim, Kyung Sung, Jang, Ji Yun, Kang, Gyeoung Jin, Lee, Ho, Won, Misun, Lee, Kyeong, Cho, Jungsook, Lee, Chang Hoon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615288/ https://www.ncbi.nlm.nih.gov/pubmed/34829545 http://dx.doi.org/10.3390/antiox10111674

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