Cargando…

Estimating Drug Efficacy with a Diet-Induced NASH Model in Chimeric Mice with Humanized Livers

Nonalcoholic fatty liver disease/steatohepatitis (NAFLD/NASH) is the most common liver disorder in developed countries. Although many new therapeutics for NASH are present in the drug development pipeline, there are still no approved drugs. One of the reasons that makes NASH drug development challen...

Descripción completa

Detalles Bibliográficos
Autores principales: Kisoh, Keishi, Sugahara, Go, Ogawa, Yuko, Furukawa, Suzue, Ishida, Yuji, Okanoue, Takeshi, Kohara, Michinori, Tateno, Chise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615377/
https://www.ncbi.nlm.nih.gov/pubmed/34829876
http://dx.doi.org/10.3390/biomedicines9111647