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Estimating Drug Efficacy with a Diet-Induced NASH Model in Chimeric Mice with Humanized Livers
Nonalcoholic fatty liver disease/steatohepatitis (NAFLD/NASH) is the most common liver disorder in developed countries. Although many new therapeutics for NASH are present in the drug development pipeline, there are still no approved drugs. One of the reasons that makes NASH drug development challen...
Autores principales: | Kisoh, Keishi, Sugahara, Go, Ogawa, Yuko, Furukawa, Suzue, Ishida, Yuji, Okanoue, Takeshi, Kohara, Michinori, Tateno, Chise |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615377/ https://www.ncbi.nlm.nih.gov/pubmed/34829876 http://dx.doi.org/10.3390/biomedicines9111647 |
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