Sex-Specific Metabolic Pathways Were Associated with Alzheimer’s Disease (AD) Endophenotypes in the European Medical Information Framework for AD Multimodal Biomarker Discovery Cohort

Background: physiological differences between males and females could contribute to the development of Alzheimer’s Disease (AD). Here, we examined metabolic pathways that may lead to precision medicine initiatives. Methods: We explored whether sex modifies the association of 540 plasma metabolites w...

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Detalles Bibliográficos
Autores principales: Xu, Jin, Green, Rebecca, Kim, Min, Lord, Jodie, Ebshiana, Amera, Westwood, Sarah, Baird, Alison L., Nevado-Holgado, Alejo J., Shi, Liu, Hye, Abdul, Snowden, Stuart G., Bos, Isabelle, Vos, Stephanie J. B., Vandenberghe, Rik, Teunissen, Charlotte E., Kate, Mara Ten, Scheltens, Philip, Gabel, Silvy, Meersmans, Karen, Blin, Olivier, Richardson, Jill, De Roeck, Ellen Elisa, Engelborghs, Sebastiaan, Sleegers, Kristel, Bordet, Régis, Rami, Lorena, Kettunen, Petronella, Tsolaki, Magda, Verhey, Frans R. J., Alcolea, Daniel, Lleó, Alberto, Peyratout, Gwendoline, Tainta, Mikel, Johannsen, Peter, Freund-Levi, Yvonne, Frölich, Lutz, Dobricic, Valerija, Frisoni, Giovanni B., Molinuevo, José Luis, Wallin, Anders, Popp, Julius, Martinez-Lage, Pablo, Bertram, Lars, Blennow, Kaj, Zetterberg, Henrik, Streffer, Johannes, Visser, Pieter Jelle, Lovestone, Simon, Proitsi, Petroula, Legido-Quigley, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615383/
https://www.ncbi.nlm.nih.gov/pubmed/34829839
http://dx.doi.org/10.3390/biomedicines9111610

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