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Analysis of KRAS Mutation Subtype in Tissue DNA and Cell-Free DNA Using Droplet Digital PCR and the Function of Cell-Free DNA as a Recurrence Predictive Marker in Pancreatic Cancer

KRAS mutation is a major regulator in the tumor progression of pancreatic cancer. Here, we compared the frequency and mutation burden of KRAS mutation subtypes with paired tumor tissue and blood in patients and examined their clinical significance. DNA from tumor tissues and cell-free DNA (cfDNA) fr...

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Detalles Bibliográficos
Autores principales:	Jun, Eunsung, Koo, Bonhan, Kim, Eo Jin, Hwang, Dae Wook, Lee, Jae Hoon, Song, Ki Byung, Lee, Woohyung, Park, Yejong, Hong, Sarang, Shin, Yong, Kim, Song Cheol
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615414/ https://www.ncbi.nlm.nih.gov/pubmed/34829828 http://dx.doi.org/10.3390/biomedicines9111599

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