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ZnO Tips Dotted with Au Nanoparticles—Advanced SERS Determination of Trace Nicotine
Long-term exposure to nicotine causes a variety of human diseases, such as lung damage/adenocarcinoma, nausea and vomiting, headache, incontinence and heart failure. In this work, as a surface-enhanced Raman scattering (SERS) substrate, zinc oxide (ZnO) tips decorated with gold nanoparticles (AuNPs)...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615426/ https://www.ncbi.nlm.nih.gov/pubmed/34821681 http://dx.doi.org/10.3390/bios11110465 |
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author | Cao, Jiaying Zhai, Yan Tang, Wanxin Guo, Xiaoyu Wen, Ying Yang, Haifeng |
author_facet | Cao, Jiaying Zhai, Yan Tang, Wanxin Guo, Xiaoyu Wen, Ying Yang, Haifeng |
author_sort | Cao, Jiaying |
collection | PubMed |
description | Long-term exposure to nicotine causes a variety of human diseases, such as lung damage/adenocarcinoma, nausea and vomiting, headache, incontinence and heart failure. In this work, as a surface-enhanced Raman scattering (SERS) substrate, zinc oxide (ZnO) tips decorated with gold nanoparticles (AuNPs) are fabricated and designated as ZnO/Au. Taking advantage of the synergistic effect of a ZnO semiconductor with morphology of tips and AuNPs, the ZnO/Au-based SERS assay for nicotine demonstrates high sensitivity and the limit of detection 8.9 × 10(−12) mol/L is reached, as well as the corresponding linear dynamic detection range of 10(−10)–10(−6) mol/L. Additionally, the signal reproducibility offered by the SERS substrate could realize the reliable determination of trace nicotine in saliva. |
format | Online Article Text |
id | pubmed-8615426 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-86154262021-11-26 ZnO Tips Dotted with Au Nanoparticles—Advanced SERS Determination of Trace Nicotine Cao, Jiaying Zhai, Yan Tang, Wanxin Guo, Xiaoyu Wen, Ying Yang, Haifeng Biosensors (Basel) Communication Long-term exposure to nicotine causes a variety of human diseases, such as lung damage/adenocarcinoma, nausea and vomiting, headache, incontinence and heart failure. In this work, as a surface-enhanced Raman scattering (SERS) substrate, zinc oxide (ZnO) tips decorated with gold nanoparticles (AuNPs) are fabricated and designated as ZnO/Au. Taking advantage of the synergistic effect of a ZnO semiconductor with morphology of tips and AuNPs, the ZnO/Au-based SERS assay for nicotine demonstrates high sensitivity and the limit of detection 8.9 × 10(−12) mol/L is reached, as well as the corresponding linear dynamic detection range of 10(−10)–10(−6) mol/L. Additionally, the signal reproducibility offered by the SERS substrate could realize the reliable determination of trace nicotine in saliva. MDPI 2021-11-19 /pmc/articles/PMC8615426/ /pubmed/34821681 http://dx.doi.org/10.3390/bios11110465 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Communication Cao, Jiaying Zhai, Yan Tang, Wanxin Guo, Xiaoyu Wen, Ying Yang, Haifeng ZnO Tips Dotted with Au Nanoparticles—Advanced SERS Determination of Trace Nicotine |
title | ZnO Tips Dotted with Au Nanoparticles—Advanced SERS Determination of Trace Nicotine |
title_full | ZnO Tips Dotted with Au Nanoparticles—Advanced SERS Determination of Trace Nicotine |
title_fullStr | ZnO Tips Dotted with Au Nanoparticles—Advanced SERS Determination of Trace Nicotine |
title_full_unstemmed | ZnO Tips Dotted with Au Nanoparticles—Advanced SERS Determination of Trace Nicotine |
title_short | ZnO Tips Dotted with Au Nanoparticles—Advanced SERS Determination of Trace Nicotine |
title_sort | zno tips dotted with au nanoparticles—advanced sers determination of trace nicotine |
topic | Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615426/ https://www.ncbi.nlm.nih.gov/pubmed/34821681 http://dx.doi.org/10.3390/bios11110465 |
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