Structural and Computational Study of the GroEL–Prion Protein Complex

The molecular chaperone GroEL is designed to promote protein folding and prevent aggregation. However, the interaction between GroEL and the prion protein, PrP(C), could lead to pathogenic transformation of the latter to the aggregation-prone PrP(Sc) form. Here, the molecular basis of the interactio...

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Detalles Bibliográficos
Autores principales: Mamchur, Aleksandra A., Moiseenko, Andrei V., Panina, Irina S., Yaroshevich, Igor A., Kudryavtseva, Sofia S., Pichkur, Evgeny B., Sokolova, Olga S., Muronetz, Vladimir I., Stanishneva-Konovalova, Tatiana B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615626/
https://www.ncbi.nlm.nih.gov/pubmed/34829878
http://dx.doi.org/10.3390/biomedicines9111649

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