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A Novel Cellular Therapy to Treat Pancreatic Pain in Experimental Chronic Pancreatitis Using Human Alpha-1 Antitrypsin Overexpressing Mesenchymal Stromal Cells

Chronic pancreatitis (CP) is characterized by pancreatic inflammation, fibrosis, and abdominal pain that is challenging to treat. Mesenchymal stromal cells (MSCs) overexpressing human alpha-1 antitrypsin (hAAT-MSCs) showed improved mobility and protective functions over native MSCs in nonobese diabe...

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Detalles Bibliográficos
Autores principales: Chow, Rebecca P., Nguyen, Kevin, Gou, Wenyu, Green, Erica, Morgan, Katherine, Lancaster, William, Helke, Kristi, Strange, Charlie, Wang, Hongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615652/
https://www.ncbi.nlm.nih.gov/pubmed/34829924
http://dx.doi.org/10.3390/biomedicines9111695