Cargando…

Human iPSC-Derived Neurons as A Platform for Deciphering the Mechanisms behind Brain Aging

With an increased life expectancy among humans, aging has recently emerged as a major focus in biomedical research. The lack of in vitro aging models—especially for neurological disorders, where access to human brain tissues is limited—has hampered the progress in studies on human brain aging and va...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chao, Chuan-Chuan, Shen, Po-Wen, Tzeng, Tsai-Yu, Kung, Hsing-Jien, Tsai, Ting-Fen, Wong, Yu-Hui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615703/ https://www.ncbi.nlm.nih.gov/pubmed/34829864 http://dx.doi.org/10.3390/biomedicines9111635

Ejemplares similares

Assessing the therapeutic potential of Graptopetalum paraguayense on Alzheimer’s disease using patient iPSC-derived neurons
por: Wu, Pei-Chun, et al.
Publicado: (2019)

Understanding the genetics behind complex human disease with large-scale iPSC collections
por: Yamasaki, Amanda E., et al.
Publicado: (2017)

Pro-maturational Effects of Human iPSC-Derived Cortical Astrocytes upon iPSC-Derived Cortical Neurons
por: Hedegaard, Anne, et al.
Publicado: (2020)

Poly(ADP-ribose) polymerase 1 regulates nuclear reprogramming and promotes iPSC generation without c-Myc
por: Chiou, Shih-Hwa, et al.
Publicado: (2013)

Improved modeling of human AD with an automated culturing platform for iPSC neurons, astrocytes and microglia
por: Bassil, Reina, et al.
Publicado: (2021)

Human iPSC banking: barriers and opportunities
por: Huang, Ching-Ying, et al.
Publicado: (2019)

Identifying the dynamics of actin and tubulin polymerization in iPSCs and in iPSC-derived neurons
por: Magliocca, Valentina, et al.
Publicado: (2017)

Modeling Alzheimer’s disease with iPSC-derived brain cells
por: Penney, Jay, et al.
Publicado: (2019)

Development of a platform to investigate long-term potentiation in human iPSC-derived neuronal networks
por: Pré, Deborah, et al.
Publicado: (2022)

Development of a platform to investigate long-term potentiation in human iPSC-derived neuronal networks
por: Pré, Deborah, et al.
Publicado: (2023)

A multimodal iPSC platform for cystic fibrosis drug testing
por: Berical, Andrew, et al.
Publicado: (2022)

Molecular and functional variation in iPSC-derived sensory neurons
por: Schwartzentruber, Jeremy, et al.
Publicado: (2017)

Transcriptome Dynamics of Human Neuronal Differentiation From iPSC
por: Kuruş, Meltem, et al.
Publicado: (2021)

Utility of iPSC-Derived Cells for Disease Modeling, Drug Development, and Cell Therapy
por: Nicholson, Martin W., et al.
Publicado: (2022)

High-content analysis of neuronal morphology in human iPSC-derived neurons
por: Lickfett, Selene, et al.
Publicado: (2022)

Deciphering tau-related dementia using human iPSC lines: electrophysiological perspectives of future studies
por: Kopach, Olga
Publicado: (2022)

Interactive deciphering electron-shuttling characteristics of agricultural wastes with potential bioenergy-steered anti-COVID-19 activity via microbial fuel cells
por: Tsai, Po-Wei, et al.
Publicado: (2022)

Muscle atrophy‐related myotube‐derived exosomal microRNA in neuronal dysfunction: Targeting both coding and long noncoding RNAs
por: Yang, Chia‐Pei, et al.
Publicado: (2020)

iPSC-Derived Hepatocytes as a Platform for Disease Modeling and Drug Discovery
por: Corbett, James L., et al.
Publicado: (2019)

Using Human iPSC-Derived Neurons to Model TAU Aggregation
por: Verheyen, An, et al.
Publicado: (2015)

Quantitative proteomic analysis of Rett iPSC-derived neuronal progenitors
por: Varderidou-Minasian, Suzy, et al.
Publicado: (2020)

Preparation and Co‐Culture of iPSC‐Derived Dopaminergic Neurons and Astrocytes
por: de Rus Jacquet, Aurelie
Publicado: (2019)

Human iPSC-Derived Cortical Neurons Display Homeostatic Plasticity
por: Cordella, Federica, et al.
Publicado: (2022)

Automated high-content imaging in iPSC-derived neuronal progenitors
por: Papandreou, Apostolos, et al.
Publicado: (2023)

Cells derived from iPSC can be immunogenic — Yes or No?
por: Cao, Jiani, et al.
Publicado: (2014)

Astrocytes Attenuate Mitochondrial Dysfunctions in Human Dopaminergic Neurons Derived from iPSC
por: Du, Fang, et al.
Publicado: (2018)

Banking on iPSC- Is it Doable and is it Worthwhile
por: Solomon, Susan, et al.
Publicado: (2014)

Roadblocks in the Path of iPSC to the Clinic
por: Garreta, Elena, et al.
Publicado: (2018)

iPSC Bioprinting: Where are We at?
por: Romanazzo, Sara, et al.
Publicado: (2019)

Maturing iPSC-Derived Cardiomyocytes
por: Tang, Bor Luen
Publicado: (2020)

iPSC for modeling neurodegenerative disorders
por: Valadez-Barba, Valeria, et al.
Publicado: (2020)

Deciphering the Role of Wnt and Rho Signaling Pathway in iPSC-Derived ARVC Cardiomyocytes by In Silico Mathematical Modeling
por: Parrotta, Elvira Immacolata, et al.
Publicado: (2021)

A platform for rapid generation of single and multiplexed reporters in human iPSC lines
por: Pei, Ying, et al.
Publicado: (2015)

Development of iPSC-based clinical trial selection platform for patients with ultrarare diseases
por: Sequiera, Glen Lester, et al.
Publicado: (2022)

Calcium dysregulation contributes to neurodegeneration in FTLD patient iPSC-derived neurons
por: Imamura, Keiko, et al.
Publicado: (2016)

Clusterin Is Required for β-Amyloid Toxicity in Human iPSC-Derived Neurons
por: Robbins, Jacqueline P., et al.
Publicado: (2018)

Microglia Influence Neurofilament Deposition in ALS iPSC-Derived Motor Neurons
por: Allison, Reilly L., et al.
Publicado: (2022)

Continuous Monitoring of Tau-Induced Neurotoxicity in Patient-Derived iPSC-Neurons
por: Oakley, Derek H., et al.
Publicado: (2021)

Topologically controlled circuits of human iPSC-derived neurons for electrophysiology recordings
por: Girardin, Sophie, et al.
Publicado: (2022)

CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis
por: Samelson, Avi J., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_mr67ieirdau9fafd36ier2e2nh