Fabrication of Co(3)O(4)/NiCo(2)O(4) Nanocomposite for Detection of H(2)O(2) and Dopamine

Herein, the Co(3)O(4)/NiCo(2)O(4) nanocomposite has been prepared as a novel electrochemical sensor to accurately detect hydrogen peroxide (H(2)O(2)) and glucose. ZIF-67 is a metal-organic framework (MOF) with Co as the center metal ion. Co(3)O(4) can be obtained by calcination of ZIF-67 at 700 °C, which can retain the structure of ZIF-67. The hollow Co(3)O(4) nanocrystal was synthesized based on a calcination process of ZIF-67. This open structure can promote the whole Co(3)O(4)/NiCo(2)O(4) nanocomposite larger accessible surface area and reactive sites. Co(3)O(4) has good electrocatalytic performance, which has been applied in many fields. Moreover, H(2)O(2) and dopamine sensing tests indicate that the as-prepared non-enzymatic electrochemical biosensor has good detection properties. The testing results indicate the as-prepared biosensor has a wide detection range, low detection limit, high selectivity, and long-term stability. These testing results suggest the potential application in food security, biomedicine, environmental detection, and pharmaceutical analysis.