The σ1 Receptor and the HINT1 Protein Control α2δ1 Binding to Glutamate NMDA Receptors: Implications in Neuropathic Pain

Nerve injury produces neuropathic pain through the binding of α2δ1 proteins to glutamate N-methyl-D-aspartate receptors (NMDARs). Notably, mice with a targeted deletion of the sigma 1 receptor (σ1R) gene do not develop neuropathy, whereas mice lacking the histidine triad nucleotide-binding protein 1...

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Detalles Bibliográficos
Autores principales: Rodríguez-Muñoz, María, Cortés-Montero, Elsa, Onetti, Yara, Sánchez-Blázquez, Pilar, Garzón-Niño, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615847/
https://www.ncbi.nlm.nih.gov/pubmed/34827679
http://dx.doi.org/10.3390/biom11111681

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615847/
https://www.ncbi.nlm.nih.gov/pubmed/34827679
http://dx.doi.org/10.3390/biom11111681

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