Cargando…

Mitochondrial Electron Transport Chain Protein Abnormalities Detected in Plasma Extracellular Vesicles in Alzheimer’s Disease

Mitochondria provide energy to neurons through oxidative phosphorylation and eliminate Reactive Oxygen Species (ROS) through Superoxide Dismutase 1 (SOD1). Dysfunctional mitochondria, manifesting decreased activity of electron transport chain (ETC) complexes and high ROS levels, are involved in Alzh...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yao, Pamela J., Eren, Erden, Goetzl, Edward J., Kapogiannis, Dimitrios
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615874/ https://www.ncbi.nlm.nih.gov/pubmed/34829816 http://dx.doi.org/10.3390/biomedicines9111587

Ejemplares similares

Abnormal levels of mitochondrial proteins in plasma neuronal extracellular vesicles in major depressive disorder
por: Goetzl, Edward J., et al.
Publicado: (2021)

Astrocyte- and Neuron-Derived Extracellular Vesicles from Alzheimer’s Disease Patients Effect Complement-Mediated Neurotoxicity
por: Nogueras-Ortiz, Carlos J., et al.
Publicado: (2020)

Prediction of Post-Acute-Sequelae of COVID-19 by Cargo Protein Biomarkers of Blood Total Extracellular Vesicles in Acute COVID-19
por: Goetzl, Edward J., et al.
Publicado: (2023)

Mitochondrial RNA in Alzheimer’s Disease Circulating Extracellular Vesicles
por: Kim, Kyoung Mi, et al.
Publicado: (2020)

Plasma Extracellular Vesicles Enriched for Neuronal Origin: A Potential Window into Brain Pathologic Processes
por: Mustapic, Maja, et al.
Publicado: (2017)

Neuron-derived extracellular vesicles in blood reveal effects of exercise in Alzheimer’s disease
por: Delgado-Peraza, Francheska, et al.
Publicado: (2023)

Neuronal and Astrocytic Extracellular Vesicle Biomarkers in Blood Reflect Brain Pathology in Mouse Models of Alzheimer’s Disease
por: Delgado-Peraza, Francheska, et al.
Publicado: (2021)

Extracellular vesicle biomarkers of Alzheimer's disease associated with sub‐clinical cognitive decline in late middle age
por: Eren, Erden, et al.
Publicado: (2020)

Mitochondrial Protrusions in Neuronal Cells
por: Yao, Pamela J., et al.
Publicado: (2020)

Altered Functional Mitochondrial Protein Levels in Plasma Neuron-Derived Extracellular Vesicles of Patients With Gadolinium Deposition
por: Goetzl, Edward J., et al.
Publicado: (2022)

Long-COVID: Phase 2 of the COVID-19 Pandemic
por: Goetzl, Edward J., et al.
Publicado: (2022)

Neuronal-Derived EV Biomarkers Track Cognitive Decline in Alzheimer’s Disease
por: Eren, Erden, et al.
Publicado: (2022)

Biomarker-Drug and Liquid Biopsy Co-development for Disease Staging and Targeted Therapy: Cornerstones for Alzheimer’s Precision Medicine and Pharmacology
por: Hampel, Harald, et al.
Publicado: (2019)

Decreased mitochondrial electron transport proteins and increased complement mediators in plasma neural-derived exosomes of early psychosis
por: Goetzl, Edward J., et al.
Publicado: (2020)

Magnetic resonance spectroscopy reveals abnormalities of glucose metabolism in the Alzheimer's brain
por: Mullins, Roger, et al.
Publicado: (2018)

Comparative assessment of Alzheimer’s disease-related biomarkers in plasma and neuron-derived extracellular vesicles: a nested case-control study
por: Manolopoulos, Apostolos, et al.
Publicado: (2023)

Cryo-electron microscopy of extracellular vesicles in fresh plasma
por: Yuana, Yuana, et al.
Publicado: (2013)

Oral nicotinamide riboside raises NAD+ and lowers biomarkers of neurodegenerative pathology in plasma extracellular vesicles enriched for neuronal origin
por: Vreones, Michael, et al.
Publicado: (2022)

Extracellular vesicles and Alzheimer’s disease in the novel era of Precision Medicine: implications for disease progression, diagnosis and treatment
por: Gomes, Patrícia, et al.
Publicado: (2022)

Structure and mechanism of mitochondrial electron transport chain
por: Guo, Runyu, et al.
Publicado: (2018)

Neuron-Derived Exosome Proteins May Contribute to Progression From Repetitive Mild Traumatic Brain Injuries to Chronic Traumatic Encephalopathy
por: Goetzl, Edward J., et al.
Publicado: (2019)

Altered Levels of Toll-Like Receptors in Circulating Extracellular Vesicles in Multiple Sclerosis
por: Bhargava, Pavan, et al.
Publicado: (2019)

Complement protein levels in plasma astrocyte-derived exosomes are abnormal in conversion from mild cognitive impairment to Alzheimer's disease dementia
por: Winston, Charisse N., et al.
Publicado: (2019)

Neurofilament light chain level in plasma extracellular vesicles and Parkinson’s disease
por: Chung, Chen-Chih, et al.
Publicado: (2020)

Low neural exosomal levels of cellular survival factors in Alzheimer’s disease
por: Goetzl, Edward J, et al.
Publicado: (2015)

Analysis of mitochondrial respiration and ATP synthase in frozen brain tissues
por: Yao, Pamela J., et al.
Publicado: (2023)

HIV Replication Increases the Mitochondrial DNA Content of Plasma Extracellular Vesicles
por: Bazié, Wilfried Wenceslas, et al.
Publicado: (2023)

Urinary extracellular vesicles and tubular transport
por: Rudolphi, Crissy F, et al.
Publicado: (2022)

Detection of Aggregation-Competent Tau in Neuron-Derived Extracellular Vesicles
por: Guix, Francesc X., et al.
Publicado: (2018)

Extracellular Vesicles as Drug Transporters
por: Nowak, Monika, et al.
Publicado: (2023)

An Abnormal Host/Microbiomes Signature of Plasma-Derived Extracellular Vesicles Is Associated to Polycythemia Vera
por: Barone, Monica, et al.
Publicado: (2021)

Abnormal accumulation of extracellular vesicles in hippocampal dystrophic axons and regulation by the primary cilia in Alzheimer’s disease
por: Jang, Jaemyung, et al.
Publicado: (2023)

Plasma extracellular vesicles from the periphery as spreading vectors of Alzheimer's disease pathogenesis?
por: Vincent, Bruno
Publicado: (2022)

Insights into the post-transcriptional regulation of the mitochondrial electron transport chain
por: Sirey, Tamara M., et al.
Publicado: (2016)

Mitochondrial electron transport chain, ROS generation and uncoupling (Review)
por: Zhao, Ru-Zhou, et al.
Publicado: (2019)

Cadmium-Induced Cytotoxicity: Effects on Mitochondrial Electron Transport Chain
por: Branca, Jacopo Junio Valerio, et al.
Publicado: (2020)

Extracellular vesicle-associated Aβ mediates trans-neuronal bioenergetic and Ca(2+)-handling deficits in Alzheimer’s disease models
por: Eitan, Erez, et al.
Publicado: (2016)

Analysis of Plasmodium falciparum Mitochondrial Electron Transport Chain Activity Using Seahorse XFe96 Extracellular Flux Assays
por: Ramesh, SaiShyam, et al.
Publicado: (2023)

Transcriptional landscape of mitochondrial electron transport chain inhibition in renal cells
por: Carta, Giada, et al.
Publicado: (2023)

Differential requirements for mitochondrial electron transport chain components in the adult murine liver
por: Lesner, Nicholas P, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_273tm6gsdqpvgbdkmfdc5se661