Similarities in DSG1 and KRT3 Downregulation through Retinoic Acid Treatment and PAX6 Knockdown Related Expression Profiles: Does PAX6 Affect RA Signaling in Limbal Epithelial Cells?

Congenital PAX6-aniridia is a rare panocular disease resulting from limbal stem cell deficiency. In PAX6-aniridia, the downregulation of the retinol-metabolizing enzymes ADH7 (All-trans-retinol dehydrogenase 7) and ALDH1A1/A3 (Retinal dehydrogenase 1, Aldehyde dehydrogenase family 1 member A3) have...

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Detalles Bibliográficos
Autores principales: Latta, Lorenz, Knebel, Igor, Bleil, Constanze, Stachon, Tanja, Katiyar, Priya, Zussy, Claire, Fries, Fabian Norbert, Käsmann-Kellner, Barbara, Seitz, Berthold, Szentmáry, Nóra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615883/
https://www.ncbi.nlm.nih.gov/pubmed/34827649
http://dx.doi.org/10.3390/biom11111651

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