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Complement Factor H Loss in RPE Cells Causes Retinal Degeneration in a Human RPE-Porcine Retinal Explant Co-Culture Model
Age-related Macular degeneration (AMD) is a degenerative disease of the macula affecting the elderly population. Treatment options are limited, partly due to the lack of understanding of AMD pathology and the lack of suitable research models that replicate the complexity of the human macula and the...
Autores principales: | Armento, Angela, Murali, Aparna, Marzi, Julia, Almansa-Garcia, Ana C, Arango-Gonzalez, Blanca, Kilger, Ellen, Clark, Simon J, Schenke-Layland, Katja, Ramlogan-Steel, Charmaine A, Steel, Jason C, Ueffing, Marius |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615889/ https://www.ncbi.nlm.nih.gov/pubmed/34827622 http://dx.doi.org/10.3390/biom11111621 |
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