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Numerical Study of Graphene/Au/SiC Waveguide-Based Surface Plasmon Resonance Sensor

A new waveguide-based surface plasmon resonance (SPR) sensor was proposed and investigated by numerical simulation. The sensor consists of a graphene cover layer, a gold (Au) thin film, and a silicon carbide (SiC) waveguide layer on a silicon dioxide/silicon (SiO(2)/Si) substrate. The large bandgap...

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Detalles Bibliográficos
Autores principales: Du, Wei, Miller, Lucas, Zhao, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615979/
https://www.ncbi.nlm.nih.gov/pubmed/34821671
http://dx.doi.org/10.3390/bios11110455
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author Du, Wei
Miller, Lucas
Zhao, Feng
author_facet Du, Wei
Miller, Lucas
Zhao, Feng
author_sort Du, Wei
collection PubMed
description A new waveguide-based surface plasmon resonance (SPR) sensor was proposed and investigated by numerical simulation. The sensor consists of a graphene cover layer, a gold (Au) thin film, and a silicon carbide (SiC) waveguide layer on a silicon dioxide/silicon (SiO(2)/Si) substrate. The large bandgap energy of SiC allows the sensor to operate in the visible and near-infrared wavelength ranges, which effectively reduces the light absorption in water to improve the sensitivity. The sensor was characterized by comparing the shift of the resonance wavelength peak with change of the refractive index (RI), which mimics the change of analyte concentration in the sensing medium. The study showed that in the RI range of 1.33~1.36, the sensitivity was improved when the graphene layers were increased. With 10 graphene layers, a sensitivity of 2810 nm/RIU (refractive index unit) was achieved, corresponding to a 39.1% improvement in sensitivity compared to the Au/SiC sensor without graphene. These results demonstrate that the graphene/Au/SiC waveguide SPR sensor has a promising use in portable biosensors for chemical and biological sensing applications, such as detection of water contaminations (RI = 1.33~1.34), hepatitis B virus (HBV), and glucose (RI = 1.34~1.35), and plasma and white blood cells (RI = 1.35~1.36) for human health and disease diagnosis.
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spelling pubmed-86159792021-11-26 Numerical Study of Graphene/Au/SiC Waveguide-Based Surface Plasmon Resonance Sensor Du, Wei Miller, Lucas Zhao, Feng Biosensors (Basel) Communication A new waveguide-based surface plasmon resonance (SPR) sensor was proposed and investigated by numerical simulation. The sensor consists of a graphene cover layer, a gold (Au) thin film, and a silicon carbide (SiC) waveguide layer on a silicon dioxide/silicon (SiO(2)/Si) substrate. The large bandgap energy of SiC allows the sensor to operate in the visible and near-infrared wavelength ranges, which effectively reduces the light absorption in water to improve the sensitivity. The sensor was characterized by comparing the shift of the resonance wavelength peak with change of the refractive index (RI), which mimics the change of analyte concentration in the sensing medium. The study showed that in the RI range of 1.33~1.36, the sensitivity was improved when the graphene layers were increased. With 10 graphene layers, a sensitivity of 2810 nm/RIU (refractive index unit) was achieved, corresponding to a 39.1% improvement in sensitivity compared to the Au/SiC sensor without graphene. These results demonstrate that the graphene/Au/SiC waveguide SPR sensor has a promising use in portable biosensors for chemical and biological sensing applications, such as detection of water contaminations (RI = 1.33~1.34), hepatitis B virus (HBV), and glucose (RI = 1.34~1.35), and plasma and white blood cells (RI = 1.35~1.36) for human health and disease diagnosis. MDPI 2021-11-15 /pmc/articles/PMC8615979/ /pubmed/34821671 http://dx.doi.org/10.3390/bios11110455 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Du, Wei
Miller, Lucas
Zhao, Feng
Numerical Study of Graphene/Au/SiC Waveguide-Based Surface Plasmon Resonance Sensor
title Numerical Study of Graphene/Au/SiC Waveguide-Based Surface Plasmon Resonance Sensor
title_full Numerical Study of Graphene/Au/SiC Waveguide-Based Surface Plasmon Resonance Sensor
title_fullStr Numerical Study of Graphene/Au/SiC Waveguide-Based Surface Plasmon Resonance Sensor
title_full_unstemmed Numerical Study of Graphene/Au/SiC Waveguide-Based Surface Plasmon Resonance Sensor
title_short Numerical Study of Graphene/Au/SiC Waveguide-Based Surface Plasmon Resonance Sensor
title_sort numerical study of graphene/au/sic waveguide-based surface plasmon resonance sensor
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615979/
https://www.ncbi.nlm.nih.gov/pubmed/34821671
http://dx.doi.org/10.3390/bios11110455
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