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Repeated α-GalCer Administration Induces a Type 2 Cytokine-Biased iNKT Cell Response and Exacerbates Atopic Skin Inflammation in Vα14(Tg) NC/Nga Mice

We have previously shown that Vα14 TCR Tg (Vα14(Tg)) NC/Nga (NC) mice contain increased numbers of double-negative (DN) invariant natural killer T (iNKT) cells that protect against spontaneous development of atopic dermatitis (AD). iNKT cells can regulate immune responses by producing various cytoki...

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Detalles Bibliográficos
Autores principales:	Park, Hyun Jung, Kim, Tae-Cheol, Park, Yun Hoo, Lee, Sung Won, Jeon, Jungmin, Park, Se-Ho, Van Kaer, Luc, Hong, Seokmann
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615984/ https://www.ncbi.nlm.nih.gov/pubmed/34829848 http://dx.doi.org/10.3390/biomedicines9111619

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