Cargando…

1-Formyl-β-carboline Derivatives Block Newcastle Disease Virus Proliferation through Suppressing Viral Adsorption and Entry Processes

Newcastle disease virus (NDV) is one of the highly contagious pathogens causing devastating economic effects on the global poultry industry. In the present study, three 1-formyl-β-carboline derivatives (compounds 6, 7, and 9) were found to be potent inhibitors of different genotypes of NDV with IC(5...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Chongyang, Wang, Ting, Dai, Jiangkun, An, Zhiyuan, Hu, Ruochen, Duan, Liuyuan, Chen, Hui, Wang, Xiangwei, Chu, Zhili, Liu, Haijin, Wang, Juan, Li, Na, Yang, Zengqi, Wang, Junru
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616010/ https://www.ncbi.nlm.nih.gov/pubmed/34827684 http://dx.doi.org/10.3390/biom11111687

Ejemplares similares

A bivalent β-carboline derivative inhibits macropinocytosis-dependent entry of pseudorabies virus by targeting the kinase DYRK1A
por: Wang, Chongyang, et al.
Publicado: (2023)

Cyclooxygenase-2 Facilitates Newcastle Disease Virus Proliferation and Is as a Target for Canthin-6-One Antiviral Activity
por: Wang, Chongyang, et al.
Publicado: (2020)

9-Butyl-Harmol Exerts Antiviral Activity against Newcastle Disease Virus through Targeting GSK-3β and HSP90β
por: Wang, Chongyang, et al.
Publicado: (2023)

Evasion of Host Antiviral Innate Immunity by Paramyxovirus Accessory Proteins
por: Wang, Chongyang, et al.
Publicado: (2022)

Newcastle disease virus selectively infects dividing cells and promotes viral proliferation
por: Chu, Zhili, et al.
Publicado: (2019)

Newcastle Disease Virus Nonstructural V Protein Upregulates SOCS3 Expression to Facilitate Viral Replication Depending on the MEK/ERK Pathway
por: Wang, Xiangwei, et al.
Publicado: (2019)

MiR-375 Has Contrasting Effects on Newcastle Disease Virus Growth Depending on the Target Gene
por: Wang, Xinglong, et al.
Publicado: (2019)

Newcastle Disease Virus V Protein Promotes Viral Replication in HeLa Cells through the Activation of MEK/ERK Signaling
por: Chu, Zhili, et al.
Publicado: (2018)

Synthesis and In Vitro Antitumor Activity of Novel Bivalent β-Carboline-3-carboxylic Acid Derivatives with DNA as a Potential Target
por: Gu, Hongling, et al.
Publicado: (2018)

Newcastle Disease Virus V Protein Inhibits Cell Apoptosis and Promotes Viral Replication by Targeting CacyBP/SIP
por: Chu, Zhili, et al.
Publicado: (2018)

Identification of Newcastle disease virus P-gene editing using next-generation sequencing
por: CHEN, Xi, et al.
Publicado: (2020)

Full Genomic Characterization of a Lentogenic Newcastle Disease Virus Isolated from Farm-Reared Ostriches (Struthio camelus) in Northwest China
por: Ren, Shanhui, et al.
Publicado: (2017)

β-Carboline dimers inhibit the tumor proliferation by the cell cycle arrest of sarcoma through intercalating to Cyclin-A2
por: Ma, Huiya, et al.
Publicado: (2022)

Pseudosterins A–C, Three 1-Ethyl-3-formyl-β-carbolines from Pseudostellaria heterophylla and Their Cardioprotective Effects
por: Xu, Guo-Bo, et al.
Publicado: (2021)

Musashi1 inhibit the release of Newcastle disease viruses through preventing apoptosis of DF-1 cells
por: Yang, Mengqing, et al.
Publicado: (2021)

Identification of a potential neutralizing linear epitope of hemagglutinin-neuraminidase in Newcastle disease virus
por: Jin, Zhongyuan, et al.
Publicado: (2021)

Cellular CARD11 Inhibits the Fusogenic Activity of Newcastle Disease Virus via CBM Signalosome-Mediated Furin Reduction in Chicken Fibroblasts
por: Wang, Wenbin, et al.
Publicado: (2021)

Screening and mechanistic study of key sites of the hemagglutinin-neuraminidase protein related to the virulence of Newcastle disease virus
por: Yan, Chuanqi, et al.
Publicado: (2020)

Cholesterol dependence of Newcastle Disease Virus entry
por: Martín, Juan José, et al.
Publicado: (2012)

Newcastle disease virus V protein inhibits apoptosis in DF-1 cells by downregulating TXNL1
por: Wang, Caiying, et al.
Publicado: (2018)

Honokiol suppresses formyl peptide-induced human neutrophil activation by blocking formyl peptide receptor 1
por: Liu, Fu-Chao, et al.
Publicado: (2017)

Fruitful Decades for Canthin-6-ones from 1952 to 2015: Biosynthesis, Chemistry, and Biological Activities
por: Dai, Jiangkun, et al.
Publicado: (2016)

Comprehensive analysis of amino acid sequence diversity at the F protein cleavage site of Newcastle disease virus in fusogenic activity
por: Wang, Yanhong, et al.
Publicado: (2017)

Synthesis of tetrahydro-β-carbolines from 2-indolylmethyl azides and propargylic alcohols
por: Yin, Haiting, et al.
Publicado: (2021)

Copper-catalyzed formylation of alkenyl C–H bonds using BrCHCl(2) as a stoichiometric formylating reagent
por: Bao, Yan, et al.
Publicado: (2018)

The transcriptional characteristics of NADC34-like PRRSV in porcine alveolar macrophages
por: Wang, Peixin, et al.
Publicado: (2022)

β-Carbolines in Experiments on Laboratory Animals
por: Zawirska-Wojtasiak, Renata, et al.
Publicado: (2020)

Erythromycin Estolate Inhibits Zika Virus Infection by Blocking Viral Entry as a Viral Inactivator
por: Wang, Xiaohuan, et al.
Publicado: (2019)

Formylation of Amines
por: Gerack, Ciera J., et al.
Publicado: (2014)

Two mutations in the HR2 region of Newcastle disease virus fusion protein with a cleavage motif “RRQRRL” are critical for fusogenic activity
por: Wang, Yanhong, et al.
Publicado: (2017)

Rhodium‐Catalyzed Formylation of Unactivated Alkyl Chlorides to Aldehydes
por: Wang, Peng, et al.
Publicado: (2022)

Mitophagy promotes replication of oncolytic Newcastle disease virus by blocking intrinsic apoptosis in lung cancer cells
por: Meng, Gang, et al.
Publicado: (2014)

Differential activation of polymorphisms of the formyl peptide receptor by formyl peptides
por: Mills, John S.
Publicado: (2007)

An intramolecular inverse electron demand Diels–Alder approach to annulated α-carbolines
por: Ma, Zhiyuan, et al.
Publicado: (2012)

Synthesis and in silico screening of a library of β-carboline-containing compounds
por: Brummond, Kay M, et al.
Publicado: (2012)

New Admission Block at Royal Victoria Infirmary, Newcastle
Publicado: (1913)

β-Formyl- and β-Vinylporphyrins: Magic Building Blocks for Novel Porphyrin Derivatives †
por: Cerqueira, Ana F. R., et al.
Publicado: (2017)

Photocatalytic enantioselective Minisci reaction of β-carbolines and application to natural product synthesis
por: Luo, Mu-Peng, et al.
Publicado: (2022)

Antiviral and virucidal activities of lycorine on duck tembusu virus in vitro by blocking viral internalization and entry
por: Lv, Xuan, et al.
Publicado: (2021)

A Series of Beta-Carboline Derivatives Inhibit the Kinase Activity of PLKs
por: Han, Xiaomin, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_iuovvbs4ohg6homhd0of2gccb4