Anti-Aggregative Effect of the Antioxidant DJ-1 on the TPPP/p25-Derived Pathological Associations of Alpha-Synuclein

DJ-1, a multi-functional protein with antioxidant properties, protects dopaminergic neurons against Parkinson’s disease (PD). The oligomerization/assembly of alpha-synuclein (SYN), promoted by Tubulin Polymerization Promoting Protein (TPPP/p25), is fatal in the early stage of PD. The pathological as...

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Detalles Bibliográficos
Autores principales: Oláh, Judit, Lehotzky, Attila, Szénási, Tibor, Ovádi, Judit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616041/
https://www.ncbi.nlm.nih.gov/pubmed/34831132
http://dx.doi.org/10.3390/cells10112909

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616041/
https://www.ncbi.nlm.nih.gov/pubmed/34831132
http://dx.doi.org/10.3390/cells10112909

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