Cargando…

Validation of SFRP1 Promoter Hypermethylation in Plasma as a Prognostic Marker for Survival and Gemcitabine Effectiveness in Patients with Stage IV Pancreatic Adenocarcinoma

SIMPLE SUMMARY: Pancreatic adenocarcinoma (PDAC) is a disease with an incredibly grim prognosis. Most patients die within one year of receiving the diagnosis. There are currently very few tools to help the clinician decide between treatment options and evaluate prognosis at an individual level. The...

Descripción completa

Detalles Bibliográficos
Autores principales:	Stubbe, Benjamin Emil, Henriksen, Stine Dam, Madsen, Poul Henning, Larsen, Anders Christian, Krarup, Henrik Bygum, Pedersen, Inge Søkilde, Johansen, Martin Nygård, Thorlacius-Ussing, Ole
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616084/ https://www.ncbi.nlm.nih.gov/pubmed/34830873 http://dx.doi.org/10.3390/cancers13225717

Ejemplares similares

Promoter hypermethylation of SFRP1 as a prognostic and potentially predictive blood-based biomarker in patients with localized pancreatic ductal adenocarcinoma
por: Stubbe, Benjamin Emil, et al.
Publicado: (2023)

Cell-free DNA promoter hypermethylation in plasma as a predictive marker for survival of patients with pancreatic adenocarcinoma
por: Henriksen, Stine Dam, et al.
Publicado: (2017)

Cell-free DNA promoter hypermethylation in plasma as a diagnostic marker for pancreatic adenocarcinoma
por: Henriksen, Stine Dam, et al.
Publicado: (2016)

The prognostic efficacy of cell-free DNA hypermethylation in colorectal cancer
por: Rasmussen, Simon Ladefoged, et al.
Publicado: (2018)

Hypermethylated DNA, a circulating biomarker for colorectal cancer detection
por: Rasmussen, Simon Ladefoged, et al.
Publicado: (2017)

High recovery of cell-free methylated DNA based on a rapid bisulfite-treatment protocol
por: Pedersen, Inge Søkilde, et al.
Publicado: (2012)

Differential effect of surgical manipulation on gene expression in normal breast tissue and breast tumor tissue
por: Pedersen, Inge Søkilde, et al.
Publicado: (2018)

Cell-Free DNA Methylation as Blood-Based Biomarkers for Pancreatic Adenocarcinoma—A Literature Update
por: Henriksen, Stine Dam, et al.
Publicado: (2021)

Colorectal cancer detected by liquid biopsy 2 years prior to clinical diagnosis in the HUNT study
por: Brenne, Siv S., et al.
Publicado: (2023)

The Physiological and Cardiologic Effects of Long Video Gaming Sessions in Adult Males
por: Krarup, Kasper Bygum, et al.
Publicado: (2022)

In silico Identification of SFRP1 as a Hypermethylated Gene in Colorectal Cancers
por: Kim, Jongbum, et al.
Publicado: (2014)

Proteomic Characterization of Colorectal Cancer Tissue from Patients Identifies Novel Putative Protein Biomarkers
por: Ludvigsen, Maja, et al.
Publicado: (2021)

Association between SFRP promoter hypermethylation and different types of cancer: A systematic review and meta-analysis
por: Yu, Jun, et al.
Publicado: (2019)

Proteomic Characterization of Colorectal Cancer Cells versus Normal-Derived Colon Mucosa Cells: Approaching Identification of Novel Diagnostic Protein Biomarkers in Colorectal Cancer
por: Ludvigsen, Maja, et al.
Publicado: (2020)

Complement activation capacity in plasma before and during high-dose prednisolone treatment and tapering in exacerbations of Crohn's disease and ulcerative colitis
por: Zimmermann-Nielsen, Erik, et al.
Publicado: (2005)

DNA hypermethylation and decreased mRNA expression of MAL, PRIMA1, PTGDR and SFRP1 in colorectal adenoma and cancer
por: Kalmár, Alexandra, et al.
Publicado: (2015)

Promoter hypermethylation of the SFRP2 gene is a high-frequent alteration and tumor-specific epigenetic marker in human breast cancer
por: Veeck, Jürgen, et al.
Publicado: (2008)

Concurrent Hypermethylation of SFRP2 and DKK2 Activates the Wnt/β-Catenin Pathway and Is Associated with Poor Prognosis in Patients with Gastric Cancer
por: Wang, Hao, et al.
Publicado: (2017)

Optimized cultivation of Campylobacter concisus from gut mucosal biopsies in inflammatory bowel disease
por: Kirk, Karina Frahm, et al.
Publicado: (2016)

Incidental detection of colorectal lesions on (18) F-FDG-PET/CT is associated with high proportion of malignancy: A study in 549 patients
por: Kousgaard, Sabrina Just, et al.
Publicado: (2020)

Age-Dependent Increase in Incidence of Staphylococcus aureus Bacteremia, Denmark, 2008–2015
por: Thorlacius-Ussing, Louise, et al.
Publicado: (2019)

Diagnostic value of (18)F-FDG PET/CT as first choice in the detection of recurrent colorectal cancer due to rising CEA
por: Gade, Michael, et al.
Publicado: (2015)

Effects of Perioperative Supplementation with Omega-3 Fatty Acids on Leukotriene B(4) and Leukotriene B(5) Production by Stimulated Neutrophils in Patients with Colorectal Cancer: A Randomized, Placebo-Controlled Intervention Trial
por: Sorensen, Lone S., et al.
Publicado: (2014)

Study of SFRP1 and SFRP2 methylation status in patients with de novo Acute Myeloblastic Leukemia
por: Ghasemi, Ali, et al.
Publicado: (2015)

DNA methylation of SFRP1, SFRP2, and WIF1 and prognosis of postoperative colorectal cancer patients
por: Liu, Xinyan, et al.
Publicado: (2019)

Wnt pathway antagonists, SFRP1, SFRP2, SOX17, and PPP2R2B, are methylated in gliomas and SFRP1 methylation predicts shorter survival
por: Majchrzak-Celińska, Aleksandra, et al.
Publicado: (2015)

Tumor-Specific Hypermethylation of Epigenetic Biomarkers, Including SFRP1, Predicts for Poorer Survival in Patients from the TCGA Kidney Renal Clear Cell Carcinoma (KIRC) Project
por: Ricketts, Christopher J., et al.
Publicado: (2014)

The role of dexamethasone in mediating the contradictory effects of Wnt antagonists SFRP2 and SFRP3 on human hair follicle growth
por: Hamida, Ons Ben, et al.
Publicado: (2023)

Treatment of Patients with Advanced Biliary Tract Cancer with Either Oxaliplatin, Gemcitabine, and Capecitabine or Cisplatin and Gemcitabine—A Randomized Phase II Trial
por: Markussen, Alice, et al.
Publicado: (2020)

The role of Sfrp and DKK proteins in cardiomyocyte development
por: Hsueh, Ying‐Chang, et al.
Publicado: (2021)

The Microbiota Profile in Inflamed and Non-Inflamed Ileal Pouch–Anal Anastomosis
por: Kousgaard, Sabrina Just, et al.
Publicado: (2020)

Usefulness of Imaging Response Assessment after Irreversible Electroporation of Localized Pancreatic Cancer—Results from a Prospective Cohort
por: Flak, Rasmus V., et al.
Publicado: (2021)

Efficacy of seven and fourteen days of antibiotic treatment in uncomplicated Staphylococcus aureus bacteremia (SAB7): study protocol for a randomized controlled trial
por: Thorlacius-Ussing, Louise, et al.
Publicado: (2019)

Risk of hepatitis B when migrating from low to high endemic areas
por: Krarup, Henrik Bygum, et al.
Publicado: (2020)

Aberrant expression of SFRP1, SFRP3, DVL2 and DVL3 Wnt signaling pathway components in diffuse gastric carcinoma
por: Sremac, Maja, et al.
Publicado: (2021)

Molecular epidemiology and comparative genomics of Campylobacter concisus strains from saliva, faeces and gut mucosal biopsies in inflammatory bowel disease
por: Kirk, Karina Frahm, et al.
Publicado: (2018)

Proteomic Analysis of Tissue from α1,3-galactosyltransferase Knockout Mice Reveals That a Wide Variety of Proteins and Protein Fragments Change Expression Level
por: Thorlacius-Ussing, Louise, et al.
Publicado: (2013)

High serum levels of the C-propetide of type V collagen (PRO-C5) are prognostic for short overall survival in patients with pancreatic ductal adenocarcinoma
por: Nissen, Neel I., et al.
Publicado: (2023)

Promoter Methylation of SFRP3 Is Frequent in Hepatocellular Carcinoma
por: Lin, Ya-Wen, et al.
Publicado: (2014)

Expression of SFRP Family Proteins in Human Keratoconus Corneas
por: You, Jingjing, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_vctlqc41603643v1t7aikqe40l