Cargando…

Diagnostic and Prognostic Implications of Caspase-1 and PD-L1 Co-Expression Patterns in Myelodysplastic Syndromes

SIMPLE SUMMARY: Myelodysplastic syndromes (MDS) originate from mutated hematopoietic stem and progenitor cells. Despite recent advances in genetics, the mechanisms involved in clonal progression remain largely unknown. We performed an exploratory, case-control study to identify immune-related biomar...

Descripción completa

Detalles Bibliográficos
Autores principales:	Graf, Johannes R., Forster, Stefan, Bruehl, Frido K., Banz, Yara, Hallal, Mahmoud, Brodard, Justine, Bacher, Vera Ulrike, Allam, Ramanjaneyulu, Schürch, Christian M., Bonadies, Nicolas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616142/ https://www.ncbi.nlm.nih.gov/pubmed/34830867 http://dx.doi.org/10.3390/cancers13225712

Ejemplares similares

Myelodysplastic Syndromes in the Postgenomic Era and Future Perspectives for Precision Medicine
por: Chanias, Ioannis, et al.
Publicado: (2021)

Inflammasome Activation in Myeloid Malignancies—Friend or Foe?
por: Andina, Nicola, et al.
Publicado: (2022)

Inference of kinase-signaling networks in human myeloid cell line models by Phosphoproteomics using kinase activity enrichment analysis (KAEA)
por: Hallal, Mahmoud, et al.
Publicado: (2021)

Survey on Recommended Health Care for Adult Patients with Myelodysplastic Syndromes Identifies Areas for Improvement
por: Chanias, Ioannis, et al.
Publicado: (2020)

Glofitamab Treatment in Relapsed or Refractory DLBCL after CAR T-Cell Therapy
por: Rentsch, Vera, et al.
Publicado: (2022)

Rare Cytogenetic Abnormalities in Myelodysplastic Syndromes
por: Bacher, Ulrike, et al.
Publicado: (2015)

Systemic mastocytosis with an associated hematological neoplasms: One or two entities?
por: Njue, Linet, et al.
Publicado: (2020)

BeEAM High-Dose Chemotherapy with Polatuzumab (Pola-BeEAM) before ASCT in Patients with DLBCL—A Pilot Study
por: Stoffel, Tanja, et al.
Publicado: (2022)

Angiogenin (ANG)—Ribonuclease Inhibitor (RNH1) System in Protein Synthesis and Disease
por: Sarangdhar, Mayuresh Anant, et al.
Publicado: (2021)

Anti-GBM Glomerulonephritis Involves IL-1 but Is Independent of NLRP3/ASC Inflammasome-Mediated Activation of Caspase-1
por: Lichtnekert, Julia, et al.
Publicado: (2011)

LRR-protein RNH1 dampens the inflammasome activation and is associated with COVID-19 severity
por: Bombaci, Giuseppe, et al.
Publicado: (2022)

Targeting PD-1/PD-L1 pathway in myelodysplastic syndromes and acute myeloid leukemia
por: Yang, Xingcheng, et al.
Publicado: (2022)

The Role of BCL-2 and PD-1/PD-L1 Pathway in Pathogenesis of Myelodysplastic Syndromes
por: Kuszczak, Bartłomiej, et al.
Publicado: (2023)

Blinatumomab in Relapsed/Refractory Burkitt Lymphoma
por: Bohler, Jeanne, et al.
Publicado: (2022)

Outcome of Patients with Diffuse Large B-Cell Lymphoma Relapsing after Autologous Transplant before Availability of CAR-T Cell Treatment
por: von Matt, Stefanie, et al.
Publicado: (2023)

When Should We Think of Myelodysplasia or Bone Marrow Failure in a Thrombocytopenic Patient? A Practical Approach to Diagnosis
por: Bonadies, Nicolas, et al.
Publicado: (2021)

CAR T-cell therapy and critical care: A survival guide for medical emergency teams
por: Messmer, Anna S., et al.
Publicado: (2021)

Human molecular genetics sheds light on the physiological significance of ribonuclease inhibitor (RNH1)
por: Sarangdhar, Mayuresh Anant, et al.
Publicado: (2023)

Management of patients with lower-risk myelodysplastic syndromes
por: Brunner, Andrew M., et al.
Publicado: (2022)

Novel Adaptive T-Cell Oncological Treatments Lead to New Challenges for Medical Emergency Teams: A 2-Year Experience From a Tertiary-Care Hospital in Switzerland
por: Messmer, Anna Sarah, et al.
Publicado: (2021)

Combining BeEAM with Brentuximab Vedotin for High-Dose Therapy in CD30 Positive Lymphomas before Autologous Transplantation—A Phase I Study
por: Rausch, Christian, et al.
Publicado: (2022)

Evaluation of Bortezomib-BeEAM (2BeEAM) as Chemotherapy Regimen Prior to ASCT in Patients with Mantle Cell Lymphoma
por: Huwyler, Fabrizio, et al.
Publicado: (2023)

The “don't eat me” signal CD47 is a novel diagnostic biomarker and potential therapeutic target for diffuse malignant mesothelioma
por: Schürch, Christian M., et al.
Publicado: (2017)

Expression of PD-L1, PD-L2, PD-1 and CTLA4 in myelodysplastic syndromes is enhanced by treatment with hypomethylating agents
por: Yang, Hui, et al.
Publicado: (2013)

Transformed Lymphoma Is Associated with a Favorable Response to CAR-T-Cell Treatment in DLBCL Patients
por: Nydegger, Anna, et al.
Publicado: (2021)

S100A9-induced overexpression of PD-1/PD-L1 contributes to ineffective hematopoiesis in myelodysplastic syndromes
por: Cheng, Pinyang, et al.
Publicado: (2019)

Rebound Thrombocytosis after Induction Chemotherapy is a Strong Biomarker for Favorable Outcome in AML Patients
por: Schnell, Bianca R., et al.
Publicado: (2019)

Caspase-3 and Caspase-6 cleave STAT1 in leukemic cells
por: Licht, Verena, et al.
Publicado: (2014)

IgM monoclonal gammopathy of undetermined significance: clinicopathologic features with and without IgM-related disorders
por: Bruehl, Frido K., et al.
Publicado: (2023)

PB2574: HEMOPHAGOCYTIC SYNDROME IN ADULTS - REAL-WORLD DATA ON MORTALITY FROM A TERTIARY REFERENCE CENTER
por: Wojtovicova, Tatiana, et al.
Publicado: (2023)

Polyene Macrolide Antifungal Drugs Trigger Interleukin-1β Secretion by Activating the NLRP3 Inflammasome
por: Darisipudi, Murthy Narayana, et al.
Publicado: (2011)

Effect of Sample Transportation on the Proteome of Human Circulating Blood Extracellular Vesicles
por: Uldry, Anne-Christine, et al.
Publicado: (2022)

Detailed analysis of clonal evolution and cytogenetic evolution patterns in patients with myelodysplastic syndromes (MDS) and related myeloid disorders
por: Schanz, Julie, et al.
Publicado: (2018)

Analysis of the impact of adherence to guidelines and expert advice in patients with myelodysplastic syndromes
por: Kasprzak, A., et al.
Publicado: (2020)

Correlation of plasma cell assessment by phenotypic methods and molecular profiles by NGS in patients with plasma cell dyscrasias
por: Rebmann Chigrinova, Ekaterina, et al.
Publicado: (2022)

Comprehensive Laboratory Diagnostic Workup for Patients with Suspected Intraocular Lymphoma including Flow Cytometry, Molecular Genetics and Cytopathology
por: Shumilov, Evgenii, et al.
Publicado: (2022)

PD-L1 Regulates Platelet Activation and Thrombosis via Caspase-3/GSDME Pathway
por: Li, Yulong, et al.
Publicado: (2022)

Tumor-specific T cell-mediated upregulation of PD-L1 in myelodysplastic syndrome cells does not affect T-cell killing
por: Ferrari, Valentina, et al.
Publicado: (2022)

Clinical significance of SF3B1 mutations in myelodysplastic syndromes and myelodysplastic/myeloproliferative neoplasms
por: Malcovati, Luca, et al.
Publicado: (2011)

Differential roles of caspase-1 and caspase-11 in infection and inflammation
por: Ming Man, Si, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_gkf74rvrp3jenao5tdppfordgs