Cargando…
The Retinoblastoma Tumor Suppressor Is Required for the NUP98-HOXA9-Induced Aberrant Nuclear Envelope Phenotype
Chromosomal translocations involving the nucleoporin NUP98 gene are recurrently identified in leukemia; yet, the cellular defects accompanying NUP98 fusion proteins are poorly characterized. NUP98 fusions cause changes in nuclear and nuclear envelope (NE) organization, in particular, in the nuclear...
Autores principales: | Vaz, Marcela, Fahrenkrog, Birthe |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616146/ https://www.ncbi.nlm.nih.gov/pubmed/34831074 http://dx.doi.org/10.3390/cells10112851 |
Ejemplares similares
-
Expression of Leukemia-Associated Nup98 Fusion Proteins Generates an Aberrant Nuclear Envelope Phenotype
por: Fahrenkrog, Birthe, et al.
Publicado: (2016) -
Disclosing the Interactome of Leukemogenic NUP98-HOXA9 and SET-NUP214 Fusion Proteins Using a Proteomic Approach
por: Mendes, Adélia, et al.
Publicado: (2020) -
Dissection of the Transformation of Primary Human Hematopoietic Cells by the Oncogene NUP98-HOXA9
por: Yassin, Enas R., et al.
Publicado: (2009) -
The molecular pathogenesis of the NUP98-HOXA9 fusion protein in acute myeloid leukemia
por: Rio-Machin, A, et al.
Publicado: (2017) -
The nucleoporin Nup88 is interacting with nuclear lamin A
por: Lussi, Yvonne C., et al.
Publicado: (2011)