AKF-D52, a Synthetic Phenoxypyrimidine-Urea Derivative, Triggers Extrinsic/Intrinsic Apoptosis and Cytoprotective Autophagy in Human Non-Small Cell Lung Cancer Cells

SIMPLE SUMMARY: We previously reported the antiproliferative effects of a phenoxypyridine urea derivative. In this study, we aimed to investigate the antiproliferative effects of 1-(3,5-dimethoxyphenyl)-3-(4-(3-methoxyphenoxy)-2-((4-morpholinophenyl)amino)pyrimidin-5-yl)urea (AKF-D52) in non-small c...

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Detalles Bibliográficos
Autores principales: Gil, Hyo-Sun, Lee, Jeong-Hun, Farag, Ahmed K., Hassan, Ahmed H. E., Chung, Kyung-Sook, Choi, Jung-Hye, Roh, Eun-Joo, Lee, Kyung-Tae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616202/
https://www.ncbi.nlm.nih.gov/pubmed/34831003
http://dx.doi.org/10.3390/cancers13225849

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