iPSC-Derived Gaucher Macrophages Display Growth Impairment and Activation of Inflammation-Related Cell Death

Gaucher disease is a lysosomal storage disorder characterized by β-glucosidase enzyme deficiency and substrate accumulation, especially in cells of the reticuloendothelial system. Typical features of the disease are the unrestrained activation of inflammatory mechanisms, whose molecular pathways are...

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Detalles Bibliográficos
Autores principales: Messelodi, Daria, Bertuccio, Salvatore Nicola, Indio, Valentina, Strocchi, Silvia, Taddia, Alberto, Serravalle, Salvatore, Bandini, Jessica, Astolfi, Annalisa, Pession, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616237/
https://www.ncbi.nlm.nih.gov/pubmed/34831047
http://dx.doi.org/10.3390/cells10112822

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