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DNMT3A and DNMT3B Targeting as an Effective Radiosensitizing Strategy in Embryonal Rhabdomyosarcoma

Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in childhood. Recently, we demonstrated the overexpression of both DNA methyltransferase 3A (DNMT3A) and 3B (DNMT3B) in RMS tumour biopsies and cell lines compared to normal skeletal muscle. Radiotherapy may often fail due to the abnormal...

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Detalles Bibliográficos
Autores principales:	Camero, Simona, Vitali, Giulia, Pontecorvi, Paola, Ceccarelli, Simona, Anastasiadou, Eleni, Cicchetti, Francesca, Flex, Elisabetta, Pomella, Silvia, Cassandri, Matteo, Rota, Rossella, Marampon, Francesco, Marchese, Cinzia, Schiavetti, Amalia, Megiorni, Francesca
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616246/ https://www.ncbi.nlm.nih.gov/pubmed/34831178 http://dx.doi.org/10.3390/cells10112956

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