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GM101 in Combination with Histone Deacetylase Inhibitor Enhances Anti-Tumor Effects in Desmoplastic Microenvironment

Oncolytic adenoviruses (oAds) have been evaluated in numerous clinical trials due to their promising attributes as cancer therapeutics. However, the therapeutic efficacy of oAds was limited due to variable coxsackie and adenovirus receptor (CAR) expression levels and the dense extracellular matrix (...

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Detalles Bibliográficos
Autores principales: Chang, Han-Gyu, Choi, Yong-Hyeon, Hong, JinWoo, Choi, Joung-Woo, Yoon, A-Rum, Yun, Chae-Ok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616263/
https://www.ncbi.nlm.nih.gov/pubmed/34831034
http://dx.doi.org/10.3390/cells10112811