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c-Met-Specific Chimeric Antigen Receptor T Cells Demonstrate Anti-Tumor Effect in c-Met Positive Gastric Cancer

SIMPLE SUMMARY: c-Met is known to be overexpressed in gastric cancers. Here, we developed anti-c-Met CAR T cell and measured its anti-tumor efficacy in vitro and in vivo. Our anti c-Met CAR T cells have shown selective killing of c-Met overexpressed gastric cancer cells. Based on our results, we sug...

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Detalles Bibliográficos
Autores principales:	Kang, Chung Hyo, Kim, Yeongrin, Lee, Da Yeon, Choi, Sang Un, Lee, Heung Kyoung, Park, Chi Hoon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616279/ https://www.ncbi.nlm.nih.gov/pubmed/34830894 http://dx.doi.org/10.3390/cancers13225738

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