Cargando…
FGF/FGFR-Dependent Molecular Mechanisms Underlying Anti-Cancer Drug Resistance
SIMPLE SUMMARY: Deregulation of the FGF/FGFR axis is associated with many types of cancer and contributes to the development of chemoresistance, limiting the effectiveness of current treatment strategies. There are several mechanisms involved in this phenomenon, including cross-talks with other sign...
Autores principales: | Szymczyk, Jakub, Sluzalska, Katarzyna Dominika, Materla, Izabela, Opalinski, Lukasz, Otlewski, Jacek, Zakrzewska, Malgorzata |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616288/ https://www.ncbi.nlm.nih.gov/pubmed/34830951 http://dx.doi.org/10.3390/cancers13225796 |
Ejemplares similares
-
FGF1 protects FGFR1-overexpressing cancer cells against drugs targeting tubulin polymerization by activating AKT via two independent mechanisms
por: Szymczyk, Jakub, et al.
Publicado: (2022) -
High Affinity Promotes Internalization of Engineered Antibodies Targeting FGFR1
por: Opaliński, Łukasz, et al.
Publicado: (2018) -
FHF1 is a bona fide fibroblast growth factor that activates cellular signaling in FGFR-dependent manner
por: Sochacka, Martyna, et al.
Publicado: (2020) -
Nuclear Localization Sequence of FGF1 Is Not Required for Its Intracellular Anti-Apoptotic Activity in Differentiated Cells
por: Lampart, Agata, et al.
Publicado: (2022) -
Intracellular FGF1 protects cells from apoptosis through direct interaction with p53
por: Lampart, Agata, et al.
Publicado: (2023)