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Mitotic Centromere-Associated Kinesin (MCAK/KIF2C) Regulates Cell Migration and Invasion by Modulating Microtubule Dynamics and Focal Adhesion Turnover

SIMPLE SUMMARY: The microtubule (MT) cytoskeleton is a crucial factor for organized cell motility and migration of cancer as well as benign cells. Mitotic centromere-associated kinesin (MCAK/KIF2C) is a member of the kinesin-13 family, which is important for the regulation of MT dynamics. Its overex...

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Detalles Bibliográficos
Autores principales: Moon, Ha Hyung, Kreis, Nina-Naomi, Friemel, Alexandra, Roth, Susanne, Schulte, Dorothea, Solbach, Christine, Louwen, Frank, Yuan, Juping, Ritter, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616312/
https://www.ncbi.nlm.nih.gov/pubmed/34830827
http://dx.doi.org/10.3390/cancers13225673