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The Cytotoxicity and Clearance of Mutant Huntingtin and Other Misfolded Proteins

Protein misfolding and aggregation are implicated in many neurodegenerative diseases. One of these diseases is Huntington’s, which is caused by increased glutamine-encoding trinucleotide repeats within the Huntingtin gene. Like other misfolded proteins, mutated Huntingtin proteins with polyglutamine...

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Detalles Bibliográficos
Autores principales:	Folger, Austin, Wang, Yanchang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616338/ https://www.ncbi.nlm.nih.gov/pubmed/34831058 http://dx.doi.org/10.3390/cells10112835

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