Pathogenic Mitochondrial DNA Mutation Load Inversely Correlates with Malignant Features in Familial Oncocytic Parathyroid Tumors Associated with Hyperparathyroidism-Jaw Tumor Syndrome

While somatic disruptive mitochondrial DNA (mtDNA) mutations that severely affect the respiratory chain are counter-selected in most human neoplasms, they are the genetic hallmark of indolent oncocytomas, where they appear to contribute to reduce tumorigenic potential. A correlation between mtDNA mu...

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Detalles Bibliográficos
Autores principales: De Luise, Monica, Iommarini, Luisa, Marchio, Lorena, Tedesco, Greta, Coadă, Camelia Alexandra, Repaci, Andrea, Turchetti, Daniela, Tardio, Maria Lucia, Salfi, Nunzio, Pagotto, Uberto, Kurelac, Ivana, Porcelli, Anna Maria, Gasparre, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616364/
https://www.ncbi.nlm.nih.gov/pubmed/34831144
http://dx.doi.org/10.3390/cells10112920

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616364/
https://www.ncbi.nlm.nih.gov/pubmed/34831144
http://dx.doi.org/10.3390/cells10112920

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