Cargando…
Relationship between Tumor Mutational Burden, PD-L1, Patient Characteristics, and Response to Immune Checkpoint Inhibitors in Head and Neck Squamous Cell Carcinoma
SIMPLE SUMMARY: Immunotherapy has prompted a dramatic change in the management of head and neck squamous cell carcinoma (HNSCC), but the percentage of patients benefiting from treatment is limited to 20% or less. The application of precision oncology to HNSCC introduces the potential for the emergen...
Autores principales: | Burcher, Kimberly M., Lantz, Jeffrey W., Gavrila, Elena, Abreu, Arianne, Burcher, Jack T., Faucheux, Andrew T., Xie, Amy, Jackson, Clayton, Song, Alexander H., Hughes, Ryan T., Lycan, Thomas, Bunch, Paul M., Furdui, Cristina M., Topaloglu, Umit, D’Agostino, Ralph B., Zhang, Wei, Porosnicu, Mercedes |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616373/ https://www.ncbi.nlm.nih.gov/pubmed/34830888 http://dx.doi.org/10.3390/cancers13225733 |
Ejemplares similares
-
Prevalence of DNA Repair Gene Mutations in Blood and Tumor Tissue and Impact on Prognosis and Treatment in HNSCC
por: Burcher, Kimberly M., et al.
Publicado: (2021) -
In Reply: TP53 Alteration Status and Tumor Mutational Burden Score: Prevalence and Prognosis in Head and Neck Squamous Cell Carcinoma
por: Burcher, Kimberly M, et al.
Publicado: (2022) -
A Review of the Role of Oral Microbiome in the Development, Detection, and Management of Head and Neck Squamous Cell Cancers
por: Burcher, Kimberly M., et al.
Publicado: (2022) -
Exceptional response to cetuximab monotherapy after failure of immunotherapy with a checkpoint inhibitor in a patient with metastatic head and neck squamous cell cancer: case report and review of the literature
por: Bloomer, Chance H., et al.
Publicado: (2023) -
Quad-shot-immunotherapy: quad-shot radiotherapy with pembrolizumab for advanced/recurrent head and neck cancer
por: Hughes, Ryan T, et al.
Publicado: (2023)