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Kinome-Wide siRNA Screening Identifies DYRK1B as a Potential Therapeutic Target for Triple-Negative Breast Cancer Cells

SIMPLE SUMMARY: Therapeutic target is limited for patients with triple-negative breast cancer (TNBC). Through kinome-wide siRNA (709 genes) screening, DYRK1B was identified as a potential gene essential for cell proliferation and mobility of TNBC cells, particularly in DYRK1B highly expressed TNBC c...

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Detalles Bibliográficos
Autores principales:	Chang, Chia-Che, Chiu, Chien-Chih, Liu, Pei-Feng, Wu, Chih-Hsuan, Tseng, Yen-Chiang, Lee, Cheng-Hsin, Shu, Chih-Wen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616396/ https://www.ncbi.nlm.nih.gov/pubmed/34830933 http://dx.doi.org/10.3390/cancers13225779

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