A Polygenic Risk Score Predicts Incident Prostate Cancer Risk in Older Men but Does Not Select for Clinically Significant Disease

SIMPLE SUMMARY: Prostate cancer is a common disease in older men, yet current risk prediction models for prostate cancer do not discriminate between men at higher risk of aggressive, clinically significant disease compared to those with benign disease. If risk prediction models can be improved to id...

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Detalles Bibliográficos
Autores principales: Bakshi, Andrew, Riaz, Moeen, Orchard, Suzanne G., Carr, Prudence R., Joshi, Amit D., Cao, Yin, Rebello, Richard, Nguyen-Dumont, Tú, Southey, Melissa C., Millar, Jeremy L., Gately, Lucy, Gibbs, Peter, Ford, Leslie G., Parnes, Howard L., Chan, Andrew T., McNeil, John J., Lacaze, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616400/
https://www.ncbi.nlm.nih.gov/pubmed/34830967
http://dx.doi.org/10.3390/cancers13225815

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