Oncogenic KRAS Requires Complete Loss of BAP1 Function for Development of Murine Intrahepatic Cholangiocarcinoma

SIMPLE SUMMARY: Intrahepatic cholangiocarcinoma (ICC) is a primary liver cancer that currently has limited treatment options. As a result, patients with this disease generally have a poor prognosis. Previous studies have demonstrated that mutations in KRAS and loss of BRCA-1-associated protein 1 (BA...

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Autores principales: Marcus, Rebecca, Ferri-Borgogno, Sammy, Hosein, Abdel, Foo, Wai Chin, Ghosh, Bidyut, Zhao, Jun, Rajapakshe, Kimal, Brugarolas, James, Maitra, Anirban, Gupta, Sonal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616431/
https://www.ncbi.nlm.nih.gov/pubmed/34830866
http://dx.doi.org/10.3390/cancers13225709

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